Adolescent idiopathic scoliosis correction by instrumented vertebral arthrodesis with autologous bone graft from local harvesting without bone substitute use: results with mean 3 year follow-up

Purpose Bone substitutes’ advantage is enhancing arthrodesis biologic support without further autologous bone graft harvested from other skeleton sites, as from posterior iliac crests; however, in our experience, bone substitutes’ integration is often incomplete. Methods From 2012 to 2017, we operat...

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Veröffentlicht in:European spine journal 2018-06, Vol.27 (Suppl 2), p.175-181
Hauptverfasser: Crostelli, Marco, Mazza, Osvaldo, Mariani, Massimo, Mascello, Dario, Iorio, Carlo
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container_end_page 181
container_issue Suppl 2
container_start_page 175
container_title European spine journal
container_volume 27
creator Crostelli, Marco
Mazza, Osvaldo
Mariani, Massimo
Mascello, Dario
Iorio, Carlo
description Purpose Bone substitutes’ advantage is enhancing arthrodesis biologic support without further autologous bone graft harvested from other skeleton sites, as from posterior iliac crests; however, in our experience, bone substitutes’ integration is often incomplete. Methods From 2012 to 2017, we operated 108 patients by posterior instrumented vertebral arthrodesis in adolescent idiopathic scoliosis (AIS) correction, mean main curve 80° Cobb, and mean age 12 years and 6 months, with all pedicle screws instrumentation in main curve/curves area and hooks at upper tip of implant; bone graft has been harvested only at vertebral level, without bone substitutes or autologous graft from other patient sites or allogenic bone graft. We matched this group with 98 patients previously operated in which we used calcium triphosphate. Results At 3 year mean follow-up, all patients in group treated with autologous bone graft only have complete and stable arthrodesis without loss of correction (mean curve 27° Cobb) or instrumentation failure. At 6 year mean follow-up in the group treated with autologous bone graft augmented by calcium triphosphate, 96 patients have stable arthrodesis without loss of correction (mean curve 24°), 1 case has implant break, and 1 case has 8° Cobb loss of correction. Conclusion Bone substitutes are a further cost in arthrodesis surgery and suboptimal integration leaves foreign bodies on vertebras. Our experience shows that all pedicle screw instrumentation and bracing after surgery obtain stable correction showing in time a solid arthrodesis with autologous bone only, harvested at local site, without bone substitutes or further bone graft. Graphical abstract
doi_str_mv 10.1007/s00586-018-5597-x
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Methods From 2012 to 2017, we operated 108 patients by posterior instrumented vertebral arthrodesis in adolescent idiopathic scoliosis (AIS) correction, mean main curve 80° Cobb, and mean age 12 years and 6 months, with all pedicle screws instrumentation in main curve/curves area and hooks at upper tip of implant; bone graft has been harvested only at vertebral level, without bone substitutes or autologous graft from other patient sites or allogenic bone graft. We matched this group with 98 patients previously operated in which we used calcium triphosphate. Results At 3 year mean follow-up, all patients in group treated with autologous bone graft only have complete and stable arthrodesis without loss of correction (mean curve 27° Cobb) or instrumentation failure. At 6 year mean follow-up in the group treated with autologous bone graft augmented by calcium triphosphate, 96 patients have stable arthrodesis without loss of correction (mean curve 24°), 1 case has implant break, and 1 case has 8° Cobb loss of correction. Conclusion Bone substitutes are a further cost in arthrodesis surgery and suboptimal integration leaves foreign bodies on vertebras. Our experience shows that all pedicle screw instrumentation and bracing after surgery obtain stable correction showing in time a solid arthrodesis with autologous bone only, harvested at local site, without bone substitutes or further bone graft. Graphical abstract</description><identifier>ISSN: 0940-6719</identifier><identifier>EISSN: 1432-0932</identifier><identifier>DOI: 10.1007/s00586-018-5597-x</identifier><identifier>PMID: 29675675</identifier><language>eng</language><publisher>Berlin/Heidelberg: Springer Berlin Heidelberg</publisher><subject>Adolescent ; Arthrodesis ; Arthrodesis - methods ; Autografts ; Bone biomaterials ; Bone grafts ; Bone surgery ; Bone Transplantation - methods ; Calcium ; Child ; Follow-Up Studies ; Foreign bodies ; Humans ; Integration ; Medicine ; Medicine &amp; Public Health ; Neurosurgery ; Original Article ; Pedicle Screws ; Phosphates ; Scoliosis ; Scoliosis - surgery ; Skeleton ; Skin &amp; tissue grafts ; Surgical Orthopedics ; Transplantation, Autologous - methods ; Treatment Outcome ; Vertebrae</subject><ispartof>European spine journal, 2018-06, Vol.27 (Suppl 2), p.175-181</ispartof><rights>Springer-Verlag GmbH Germany, part of Springer Nature 2018</rights><rights>European Spine Journal is a copyright of Springer, (2018). All Rights Reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c372t-335ff487dfdc537afb76f0f3fd718e076b49fdf761ed789ffd42ddef3fa8a1563</citedby><cites>FETCH-LOGICAL-c372t-335ff487dfdc537afb76f0f3fd718e076b49fdf761ed789ffd42ddef3fa8a1563</cites><orcidid>0000-0002-1850-2864</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s00586-018-5597-x$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s00586-018-5597-x$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,780,784,27924,27925,41488,42557,51319</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/29675675$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Crostelli, Marco</creatorcontrib><creatorcontrib>Mazza, Osvaldo</creatorcontrib><creatorcontrib>Mariani, Massimo</creatorcontrib><creatorcontrib>Mascello, Dario</creatorcontrib><creatorcontrib>Iorio, Carlo</creatorcontrib><title>Adolescent idiopathic scoliosis correction by instrumented vertebral arthrodesis with autologous bone graft from local harvesting without bone substitute use: results with mean 3 year follow-up</title><title>European spine journal</title><addtitle>Eur Spine J</addtitle><addtitle>Eur Spine J</addtitle><description>Purpose Bone substitutes’ advantage is enhancing arthrodesis biologic support without further autologous bone graft harvested from other skeleton sites, as from posterior iliac crests; however, in our experience, bone substitutes’ integration is often incomplete. Methods From 2012 to 2017, we operated 108 patients by posterior instrumented vertebral arthrodesis in adolescent idiopathic scoliosis (AIS) correction, mean main curve 80° Cobb, and mean age 12 years and 6 months, with all pedicle screws instrumentation in main curve/curves area and hooks at upper tip of implant; bone graft has been harvested only at vertebral level, without bone substitutes or autologous graft from other patient sites or allogenic bone graft. We matched this group with 98 patients previously operated in which we used calcium triphosphate. Results At 3 year mean follow-up, all patients in group treated with autologous bone graft only have complete and stable arthrodesis without loss of correction (mean curve 27° Cobb) or instrumentation failure. At 6 year mean follow-up in the group treated with autologous bone graft augmented by calcium triphosphate, 96 patients have stable arthrodesis without loss of correction (mean curve 24°), 1 case has implant break, and 1 case has 8° Cobb loss of correction. Conclusion Bone substitutes are a further cost in arthrodesis surgery and suboptimal integration leaves foreign bodies on vertebras. Our experience shows that all pedicle screw instrumentation and bracing after surgery obtain stable correction showing in time a solid arthrodesis with autologous bone only, harvested at local site, without bone substitutes or further bone graft. 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Mazza, Osvaldo ; Mariani, Massimo ; Mascello, Dario ; Iorio, Carlo</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c372t-335ff487dfdc537afb76f0f3fd718e076b49fdf761ed789ffd42ddef3fa8a1563</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2018</creationdate><topic>Adolescent</topic><topic>Arthrodesis</topic><topic>Arthrodesis - methods</topic><topic>Autografts</topic><topic>Bone biomaterials</topic><topic>Bone grafts</topic><topic>Bone surgery</topic><topic>Bone Transplantation - methods</topic><topic>Calcium</topic><topic>Child</topic><topic>Follow-Up Studies</topic><topic>Foreign bodies</topic><topic>Humans</topic><topic>Integration</topic><topic>Medicine</topic><topic>Medicine &amp; Public Health</topic><topic>Neurosurgery</topic><topic>Original Article</topic><topic>Pedicle Screws</topic><topic>Phosphates</topic><topic>Scoliosis</topic><topic>Scoliosis - surgery</topic><topic>Skeleton</topic><topic>Skin &amp; 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however, in our experience, bone substitutes’ integration is often incomplete. Methods From 2012 to 2017, we operated 108 patients by posterior instrumented vertebral arthrodesis in adolescent idiopathic scoliosis (AIS) correction, mean main curve 80° Cobb, and mean age 12 years and 6 months, with all pedicle screws instrumentation in main curve/curves area and hooks at upper tip of implant; bone graft has been harvested only at vertebral level, without bone substitutes or autologous graft from other patient sites or allogenic bone graft. We matched this group with 98 patients previously operated in which we used calcium triphosphate. Results At 3 year mean follow-up, all patients in group treated with autologous bone graft only have complete and stable arthrodesis without loss of correction (mean curve 27° Cobb) or instrumentation failure. At 6 year mean follow-up in the group treated with autologous bone graft augmented by calcium triphosphate, 96 patients have stable arthrodesis without loss of correction (mean curve 24°), 1 case has implant break, and 1 case has 8° Cobb loss of correction. Conclusion Bone substitutes are a further cost in arthrodesis surgery and suboptimal integration leaves foreign bodies on vertebras. Our experience shows that all pedicle screw instrumentation and bracing after surgery obtain stable correction showing in time a solid arthrodesis with autologous bone only, harvested at local site, without bone substitutes or further bone graft. Graphical abstract</abstract><cop>Berlin/Heidelberg</cop><pub>Springer Berlin Heidelberg</pub><pmid>29675675</pmid><doi>10.1007/s00586-018-5597-x</doi><tpages>7</tpages><orcidid>https://orcid.org/0000-0002-1850-2864</orcidid></addata></record>
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subjects Adolescent
Arthrodesis
Arthrodesis - methods
Autografts
Bone biomaterials
Bone grafts
Bone surgery
Bone Transplantation - methods
Calcium
Child
Follow-Up Studies
Foreign bodies
Humans
Integration
Medicine
Medicine & Public Health
Neurosurgery
Original Article
Pedicle Screws
Phosphates
Scoliosis
Scoliosis - surgery
Skeleton
Skin & tissue grafts
Surgical Orthopedics
Transplantation, Autologous - methods
Treatment Outcome
Vertebrae
title Adolescent idiopathic scoliosis correction by instrumented vertebral arthrodesis with autologous bone graft from local harvesting without bone substitute use: results with mean 3 year follow-up
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