Adolescent idiopathic scoliosis correction by instrumented vertebral arthrodesis with autologous bone graft from local harvesting without bone substitute use: results with mean 3 year follow-up
Purpose Bone substitutes’ advantage is enhancing arthrodesis biologic support without further autologous bone graft harvested from other skeleton sites, as from posterior iliac crests; however, in our experience, bone substitutes’ integration is often incomplete. Methods From 2012 to 2017, we operat...
Gespeichert in:
Veröffentlicht in: | European spine journal 2018-06, Vol.27 (Suppl 2), p.175-181 |
---|---|
Hauptverfasser: | , , , , |
Format: | Artikel |
Sprache: | eng |
Schlagworte: | |
Online-Zugang: | Volltext |
Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
container_end_page | 181 |
---|---|
container_issue | Suppl 2 |
container_start_page | 175 |
container_title | European spine journal |
container_volume | 27 |
creator | Crostelli, Marco Mazza, Osvaldo Mariani, Massimo Mascello, Dario Iorio, Carlo |
description | Purpose
Bone substitutes’ advantage is enhancing arthrodesis biologic support without further autologous bone graft harvested from other skeleton sites, as from posterior iliac crests; however, in our experience, bone substitutes’ integration is often incomplete.
Methods
From 2012 to 2017, we operated 108 patients by posterior instrumented vertebral arthrodesis in adolescent idiopathic scoliosis (AIS) correction, mean main curve 80° Cobb, and mean age 12 years and 6 months, with all pedicle screws instrumentation in main curve/curves area and hooks at upper tip of implant; bone graft has been harvested only at vertebral level, without bone substitutes or autologous graft from other patient sites or allogenic bone graft. We matched this group with 98 patients previously operated in which we used calcium triphosphate.
Results
At 3 year mean follow-up, all patients in group treated with autologous bone graft only have complete and stable arthrodesis without loss of correction (mean curve 27° Cobb) or instrumentation failure. At 6 year mean follow-up in the group treated with autologous bone graft augmented by calcium triphosphate, 96 patients have stable arthrodesis without loss of correction (mean curve 24°), 1 case has implant break, and 1 case has 8° Cobb loss of correction.
Conclusion
Bone substitutes are a further cost in arthrodesis surgery and suboptimal integration leaves foreign bodies on vertebras. Our experience shows that all pedicle screw instrumentation and bracing after surgery obtain stable correction showing in time a solid arthrodesis with autologous bone only, harvested at local site, without bone substitutes or further bone graft.
Graphical abstract |
doi_str_mv | 10.1007/s00586-018-5597-x |
format | Article |
fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_2028957190</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2027405494</sourcerecordid><originalsourceid>FETCH-LOGICAL-c372t-335ff487dfdc537afb76f0f3fd718e076b49fdf761ed789ffd42ddef3fa8a1563</originalsourceid><addsrcrecordid>eNp1kc-KFDEQxoMo7rj6AF4k4MVLa9Ld6XS8Lcv6Bxa86LlJdyozWdKdsZLs7ryNz7JPZsYeFQShIFD5fV8q9RHykrO3nDH5LjIm-q5ivK-EULK6f0Q2vG3qiqmmfkw2TLWs6iRXZ-RZjDeMcaFY95Sc1aqTotSGPFyY4CFOsCTqjAt7nXZuonEK3oXoIp0CIkzJhYWOB-qWmDDPhQZDbwETjKg91Zh2GAwcBXcu7ajOKfiwDTnSMSxAt6htohbDTH2YimKn8RZicsv2lyDktIIxj6WbcgKaI7ynCDH7dHKdQS-0efhxAI3UBu_DXZX3z8kTq32EF6fznHz7cPX18lN1_eXj58uL62pqZJ2qphHWtr001kyikdqOsrPMNtZI3gOT3dgqa6zsOBjZK2tNWxsDBdC95qJrzsmb1XeP4Xsuww-zK4vzXi9QPjrUrO6VKNtmBX39D3oTMi5luiMlWyZa1RaKr9SEIUYEO-zRzRoPA2fDMeBhDXgoAQ_HgIf7onl1cs7jDOaP4neiBahXIJarZQv49-n_u_4Ey065kw</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2027405494</pqid></control><display><type>article</type><title>Adolescent idiopathic scoliosis correction by instrumented vertebral arthrodesis with autologous bone graft from local harvesting without bone substitute use: results with mean 3 year follow-up</title><source>MEDLINE</source><source>SpringerLink Journals</source><creator>Crostelli, Marco ; Mazza, Osvaldo ; Mariani, Massimo ; Mascello, Dario ; Iorio, Carlo</creator><creatorcontrib>Crostelli, Marco ; Mazza, Osvaldo ; Mariani, Massimo ; Mascello, Dario ; Iorio, Carlo</creatorcontrib><description>Purpose
Bone substitutes’ advantage is enhancing arthrodesis biologic support without further autologous bone graft harvested from other skeleton sites, as from posterior iliac crests; however, in our experience, bone substitutes’ integration is often incomplete.
Methods
From 2012 to 2017, we operated 108 patients by posterior instrumented vertebral arthrodesis in adolescent idiopathic scoliosis (AIS) correction, mean main curve 80° Cobb, and mean age 12 years and 6 months, with all pedicle screws instrumentation in main curve/curves area and hooks at upper tip of implant; bone graft has been harvested only at vertebral level, without bone substitutes or autologous graft from other patient sites or allogenic bone graft. We matched this group with 98 patients previously operated in which we used calcium triphosphate.
Results
At 3 year mean follow-up, all patients in group treated with autologous bone graft only have complete and stable arthrodesis without loss of correction (mean curve 27° Cobb) or instrumentation failure. At 6 year mean follow-up in the group treated with autologous bone graft augmented by calcium triphosphate, 96 patients have stable arthrodesis without loss of correction (mean curve 24°), 1 case has implant break, and 1 case has 8° Cobb loss of correction.
Conclusion
Bone substitutes are a further cost in arthrodesis surgery and suboptimal integration leaves foreign bodies on vertebras. Our experience shows that all pedicle screw instrumentation and bracing after surgery obtain stable correction showing in time a solid arthrodesis with autologous bone only, harvested at local site, without bone substitutes or further bone graft.
Graphical abstract</description><identifier>ISSN: 0940-6719</identifier><identifier>EISSN: 1432-0932</identifier><identifier>DOI: 10.1007/s00586-018-5597-x</identifier><identifier>PMID: 29675675</identifier><language>eng</language><publisher>Berlin/Heidelberg: Springer Berlin Heidelberg</publisher><subject>Adolescent ; Arthrodesis ; Arthrodesis - methods ; Autografts ; Bone biomaterials ; Bone grafts ; Bone surgery ; Bone Transplantation - methods ; Calcium ; Child ; Follow-Up Studies ; Foreign bodies ; Humans ; Integration ; Medicine ; Medicine & Public Health ; Neurosurgery ; Original Article ; Pedicle Screws ; Phosphates ; Scoliosis ; Scoliosis - surgery ; Skeleton ; Skin & tissue grafts ; Surgical Orthopedics ; Transplantation, Autologous - methods ; Treatment Outcome ; Vertebrae</subject><ispartof>European spine journal, 2018-06, Vol.27 (Suppl 2), p.175-181</ispartof><rights>Springer-Verlag GmbH Germany, part of Springer Nature 2018</rights><rights>European Spine Journal is a copyright of Springer, (2018). All Rights Reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c372t-335ff487dfdc537afb76f0f3fd718e076b49fdf761ed789ffd42ddef3fa8a1563</citedby><cites>FETCH-LOGICAL-c372t-335ff487dfdc537afb76f0f3fd718e076b49fdf761ed789ffd42ddef3fa8a1563</cites><orcidid>0000-0002-1850-2864</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s00586-018-5597-x$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s00586-018-5597-x$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,780,784,27924,27925,41488,42557,51319</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/29675675$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Crostelli, Marco</creatorcontrib><creatorcontrib>Mazza, Osvaldo</creatorcontrib><creatorcontrib>Mariani, Massimo</creatorcontrib><creatorcontrib>Mascello, Dario</creatorcontrib><creatorcontrib>Iorio, Carlo</creatorcontrib><title>Adolescent idiopathic scoliosis correction by instrumented vertebral arthrodesis with autologous bone graft from local harvesting without bone substitute use: results with mean 3 year follow-up</title><title>European spine journal</title><addtitle>Eur Spine J</addtitle><addtitle>Eur Spine J</addtitle><description>Purpose
Bone substitutes’ advantage is enhancing arthrodesis biologic support without further autologous bone graft harvested from other skeleton sites, as from posterior iliac crests; however, in our experience, bone substitutes’ integration is often incomplete.
Methods
From 2012 to 2017, we operated 108 patients by posterior instrumented vertebral arthrodesis in adolescent idiopathic scoliosis (AIS) correction, mean main curve 80° Cobb, and mean age 12 years and 6 months, with all pedicle screws instrumentation in main curve/curves area and hooks at upper tip of implant; bone graft has been harvested only at vertebral level, without bone substitutes or autologous graft from other patient sites or allogenic bone graft. We matched this group with 98 patients previously operated in which we used calcium triphosphate.
Results
At 3 year mean follow-up, all patients in group treated with autologous bone graft only have complete and stable arthrodesis without loss of correction (mean curve 27° Cobb) or instrumentation failure. At 6 year mean follow-up in the group treated with autologous bone graft augmented by calcium triphosphate, 96 patients have stable arthrodesis without loss of correction (mean curve 24°), 1 case has implant break, and 1 case has 8° Cobb loss of correction.
Conclusion
Bone substitutes are a further cost in arthrodesis surgery and suboptimal integration leaves foreign bodies on vertebras. Our experience shows that all pedicle screw instrumentation and bracing after surgery obtain stable correction showing in time a solid arthrodesis with autologous bone only, harvested at local site, without bone substitutes or further bone graft.
Graphical abstract</description><subject>Adolescent</subject><subject>Arthrodesis</subject><subject>Arthrodesis - methods</subject><subject>Autografts</subject><subject>Bone biomaterials</subject><subject>Bone grafts</subject><subject>Bone surgery</subject><subject>Bone Transplantation - methods</subject><subject>Calcium</subject><subject>Child</subject><subject>Follow-Up Studies</subject><subject>Foreign bodies</subject><subject>Humans</subject><subject>Integration</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Neurosurgery</subject><subject>Original Article</subject><subject>Pedicle Screws</subject><subject>Phosphates</subject><subject>Scoliosis</subject><subject>Scoliosis - surgery</subject><subject>Skeleton</subject><subject>Skin & tissue grafts</subject><subject>Surgical Orthopedics</subject><subject>Transplantation, Autologous - methods</subject><subject>Treatment Outcome</subject><subject>Vertebrae</subject><issn>0940-6719</issn><issn>1432-0932</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2018</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><recordid>eNp1kc-KFDEQxoMo7rj6AF4k4MVLa9Ld6XS8Lcv6Bxa86LlJdyozWdKdsZLs7ryNz7JPZsYeFQShIFD5fV8q9RHykrO3nDH5LjIm-q5ivK-EULK6f0Q2vG3qiqmmfkw2TLWs6iRXZ-RZjDeMcaFY95Sc1aqTotSGPFyY4CFOsCTqjAt7nXZuonEK3oXoIp0CIkzJhYWOB-qWmDDPhQZDbwETjKg91Zh2GAwcBXcu7ajOKfiwDTnSMSxAt6htohbDTH2YimKn8RZicsv2lyDktIIxj6WbcgKaI7ynCDH7dHKdQS-0efhxAI3UBu_DXZX3z8kTq32EF6fznHz7cPX18lN1_eXj58uL62pqZJ2qphHWtr001kyikdqOsrPMNtZI3gOT3dgqa6zsOBjZK2tNWxsDBdC95qJrzsmb1XeP4Xsuww-zK4vzXi9QPjrUrO6VKNtmBX39D3oTMi5luiMlWyZa1RaKr9SEIUYEO-zRzRoPA2fDMeBhDXgoAQ_HgIf7onl1cs7jDOaP4neiBahXIJarZQv49-n_u_4Ey065kw</recordid><startdate>20180601</startdate><enddate>20180601</enddate><creator>Crostelli, Marco</creator><creator>Mazza, Osvaldo</creator><creator>Mariani, Massimo</creator><creator>Mascello, Dario</creator><creator>Iorio, Carlo</creator><general>Springer Berlin Heidelberg</general><general>Springer Nature B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7QP</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>M0S</scope><scope>M1P</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0002-1850-2864</orcidid></search><sort><creationdate>20180601</creationdate><title>Adolescent idiopathic scoliosis correction by instrumented vertebral arthrodesis with autologous bone graft from local harvesting without bone substitute use: results with mean 3 year follow-up</title><author>Crostelli, Marco ; Mazza, Osvaldo ; Mariani, Massimo ; Mascello, Dario ; Iorio, Carlo</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c372t-335ff487dfdc537afb76f0f3fd718e076b49fdf761ed789ffd42ddef3fa8a1563</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2018</creationdate><topic>Adolescent</topic><topic>Arthrodesis</topic><topic>Arthrodesis - methods</topic><topic>Autografts</topic><topic>Bone biomaterials</topic><topic>Bone grafts</topic><topic>Bone surgery</topic><topic>Bone Transplantation - methods</topic><topic>Calcium</topic><topic>Child</topic><topic>Follow-Up Studies</topic><topic>Foreign bodies</topic><topic>Humans</topic><topic>Integration</topic><topic>Medicine</topic><topic>Medicine & Public Health</topic><topic>Neurosurgery</topic><topic>Original Article</topic><topic>Pedicle Screws</topic><topic>Phosphates</topic><topic>Scoliosis</topic><topic>Scoliosis - surgery</topic><topic>Skeleton</topic><topic>Skin & tissue grafts</topic><topic>Surgical Orthopedics</topic><topic>Transplantation, Autologous - methods</topic><topic>Treatment Outcome</topic><topic>Vertebrae</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Crostelli, Marco</creatorcontrib><creatorcontrib>Mazza, Osvaldo</creatorcontrib><creatorcontrib>Mariani, Massimo</creatorcontrib><creatorcontrib>Mascello, Dario</creatorcontrib><creatorcontrib>Iorio, Carlo</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Calcium & Calcified Tissue Abstracts</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><jtitle>European spine journal</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Crostelli, Marco</au><au>Mazza, Osvaldo</au><au>Mariani, Massimo</au><au>Mascello, Dario</au><au>Iorio, Carlo</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Adolescent idiopathic scoliosis correction by instrumented vertebral arthrodesis with autologous bone graft from local harvesting without bone substitute use: results with mean 3 year follow-up</atitle><jtitle>European spine journal</jtitle><stitle>Eur Spine J</stitle><addtitle>Eur Spine J</addtitle><date>2018-06-01</date><risdate>2018</risdate><volume>27</volume><issue>Suppl 2</issue><spage>175</spage><epage>181</epage><pages>175-181</pages><issn>0940-6719</issn><eissn>1432-0932</eissn><abstract>Purpose
Bone substitutes’ advantage is enhancing arthrodesis biologic support without further autologous bone graft harvested from other skeleton sites, as from posterior iliac crests; however, in our experience, bone substitutes’ integration is often incomplete.
Methods
From 2012 to 2017, we operated 108 patients by posterior instrumented vertebral arthrodesis in adolescent idiopathic scoliosis (AIS) correction, mean main curve 80° Cobb, and mean age 12 years and 6 months, with all pedicle screws instrumentation in main curve/curves area and hooks at upper tip of implant; bone graft has been harvested only at vertebral level, without bone substitutes or autologous graft from other patient sites or allogenic bone graft. We matched this group with 98 patients previously operated in which we used calcium triphosphate.
Results
At 3 year mean follow-up, all patients in group treated with autologous bone graft only have complete and stable arthrodesis without loss of correction (mean curve 27° Cobb) or instrumentation failure. At 6 year mean follow-up in the group treated with autologous bone graft augmented by calcium triphosphate, 96 patients have stable arthrodesis without loss of correction (mean curve 24°), 1 case has implant break, and 1 case has 8° Cobb loss of correction.
Conclusion
Bone substitutes are a further cost in arthrodesis surgery and suboptimal integration leaves foreign bodies on vertebras. Our experience shows that all pedicle screw instrumentation and bracing after surgery obtain stable correction showing in time a solid arthrodesis with autologous bone only, harvested at local site, without bone substitutes or further bone graft.
Graphical abstract</abstract><cop>Berlin/Heidelberg</cop><pub>Springer Berlin Heidelberg</pub><pmid>29675675</pmid><doi>10.1007/s00586-018-5597-x</doi><tpages>7</tpages><orcidid>https://orcid.org/0000-0002-1850-2864</orcidid></addata></record> |
fulltext | fulltext |
identifier | ISSN: 0940-6719 |
ispartof | European spine journal, 2018-06, Vol.27 (Suppl 2), p.175-181 |
issn | 0940-6719 1432-0932 |
language | eng |
recordid | cdi_proquest_miscellaneous_2028957190 |
source | MEDLINE; SpringerLink Journals |
subjects | Adolescent Arthrodesis Arthrodesis - methods Autografts Bone biomaterials Bone grafts Bone surgery Bone Transplantation - methods Calcium Child Follow-Up Studies Foreign bodies Humans Integration Medicine Medicine & Public Health Neurosurgery Original Article Pedicle Screws Phosphates Scoliosis Scoliosis - surgery Skeleton Skin & tissue grafts Surgical Orthopedics Transplantation, Autologous - methods Treatment Outcome Vertebrae |
title | Adolescent idiopathic scoliosis correction by instrumented vertebral arthrodesis with autologous bone graft from local harvesting without bone substitute use: results with mean 3 year follow-up |
url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-25T19%3A59%3A46IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Adolescent%20idiopathic%20scoliosis%20correction%20by%20instrumented%20vertebral%20arthrodesis%20with%20autologous%20bone%20graft%20from%20local%20harvesting%20without%20bone%20substitute%20use:%20results%20with%20mean%203%C2%A0year%20follow-up&rft.jtitle=European%20spine%20journal&rft.au=Crostelli,%20Marco&rft.date=2018-06-01&rft.volume=27&rft.issue=Suppl%202&rft.spage=175&rft.epage=181&rft.pages=175-181&rft.issn=0940-6719&rft.eissn=1432-0932&rft_id=info:doi/10.1007/s00586-018-5597-x&rft_dat=%3Cproquest_cross%3E2027405494%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2027405494&rft_id=info:pmid/29675675&rfr_iscdi=true |