Lacunar Stroke, Cavernous Angioma, and Fusiform Aneurysm Due to Irradiation for Pilocytic Astrocytoma—A Case Report

Radiotherapy is a useful modality for the treatment of brain tumors, but may induce brain degeneration, tumor formation, and vasculopathy in the irradiated field. We describe a rare case of a pediatric patient who presented multiple different types of vascular events consecutively in the irradiated...

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Veröffentlicht in:Journal of stroke and cerebrovascular diseases 2018-08, Vol.27 (8), p.e165-e167
Hauptverfasser: Kunitaka, Maruyama, Akai, Takuya, Akioka, Naoki, Tomita, Takahiro, Nagai, Shoichi, Kuroda, Satoshi
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container_end_page e167
container_issue 8
container_start_page e165
container_title Journal of stroke and cerebrovascular diseases
container_volume 27
creator Kunitaka, Maruyama
Akai, Takuya
Akioka, Naoki
Tomita, Takahiro
Nagai, Shoichi
Kuroda, Satoshi
description Radiotherapy is a useful modality for the treatment of brain tumors, but may induce brain degeneration, tumor formation, and vasculopathy in the irradiated field. We describe a rare case of a pediatric patient who presented multiple different types of vascular events consecutively in the irradiated field including lacunar stroke because of occlusion of perforating artery, intraventricular hemorrhage from cavernoma, and subarachnoid hemorrhage because of the rupture of fusiform aneurysm, 6 years after radiotherapy against pilocytic astrocytoma. The life-threatening aneurysm was resected, and its histologic findings revealed the radiation-induced vasculopathy. We should avoid irradiation, and repeat surgical resection for the pediatric cases with pilocytic astrocytoma. Once irradiation was indicated for them, however, we should carefully follow-up not only tumor recurrence but also angiograms to predict any cerebrovascular events.
doi_str_mv 10.1016/j.jstrokecerebrovasdis.2018.02.062
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source Elsevier ScienceDirect Journals
subjects aneurysm
cavernoma
pilocytic astrocytoma
Radiation
stroke
vasculopathy
title Lacunar Stroke, Cavernous Angioma, and Fusiform Aneurysm Due to Irradiation for Pilocytic Astrocytoma—A Case Report
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