An asymmetric chitosan scaffold for tendon tissue engineering: In vitro and in vivo evaluation with rat tendon stem/progenitor cells

[Display omitted] The poor healing capacity and typically incomplete regeneration of injured tendons has made tendon repair as a primary clinical concern. Several methods for repairing injured tendons have been developed in the last decade. Tendon regeneration using current tissue engineering techni...

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Veröffentlicht in:	Acta biomaterialia 2018-06, Vol.73, p.377-387
Hauptverfasser:	Chen, Erman, Yang, Ling, Ye, Chenyi, Zhang, Wei, Ran, Jisheng, Xue, Deting, Wang, Zhengke, Pan, Zhijun, Hu, Qiaoling
Format:	Artikel
Sprache:	eng
Schlagworte:	Achilles tendon Adhesion Asymmetric structure Asymmetric structures Asymmetry Biomaterials Biomedical materials Cells (biology) Chitosan Chitosan scaffold Collagen Collagen (type I) Collagen (type III) Elongation Fibers Gene expression Genes Healing Histology Immunofluorescence Immunohistochemistry Implantation Injuries Mechanical measurement Progenitor cells Proteins Regeneration Repair Rodents Scaffolds Stem cells Surgical implants Synergistic effect Tendon repair Tendons Tissue engineering TSPCs
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