Bacterial derived proteoliposome as ideal delivery system and cellular adjuvant

We explored the potential of a proteoliposome (PL) from the outer membrane of N. meningitidis B, as an immunopotentiator and as a vector for antigen delivery to dendritic cells (DC). DC were incubated with PL resulting in up-regulation of MHC-II, CD40, CD80, and CD86 expression and production of TNF...

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Veröffentlicht in:Vaccine 2006-04, Vol.24, p.S24-S25
Hauptverfasser: Rodríguez, Tamara, Pérez, Oliver, Ugrinovic, Sanja, Bracho, Gustavo, Mastroeni, Pietro
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Sprache:eng
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