Ganglioside GM3 is involved in neuronal cell death

Gangliosides abundant in the nervous system have been implicated in a broad range of biological functions, including the regulation of cell proliferation and death. Glutamate-induced cell death, which is accompanied by an accumulation of reactive oxygen species (ROS), is a major contributor to patho...

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Veröffentlicht in:	The FASEB journal 2006-06, Vol.20 (8), p.1248-1250
Hauptverfasser:	Sohn, Hosung, Kim, Yong-Sam, Kim, Hyun-Taek, Kim, Cheol-Hee, Cho, Eun-Wie, Kang, Hye-Yeon, Kim, Nam-Soon, Kim, Cheorl-Ho, Ryu, Seong Eon, Lee, Jeong-Hwa, Ko, Jeong Heon
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Animals Apoptosis Arachidonate 12-Lipoxygenase - metabolism Calcium - metabolism Cell Line Danio rerio G(M3) Ganglioside - antagonists & inhibitors G(M3) Ganglioside - physiology G(M3) Ganglioside - toxicity Glutamic Acid - toxicity Hippocampus - cytology Membrane Microdomains - enzymology Mice Molecular Sequence Data Neurons - cytology Neurons - drug effects Neurons - metabolism Reactive Oxygen Species - metabolism RNA Interference Sequence Alignment Sialyltransferases - antagonists & inhibitors Sialyltransferases - genetics Zebrafish - metabolism Zebrafish Proteins - genetics Zebrafish Proteins - metabolism
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