Lung Deposition of Radiolabeled Tiotropium in Healthy Subjects and Patients With Chronic Obstructive Pulmonary Disease

Lung deposition of 18 μg tiotropium administered via a dry‐powder inhaler was investigated in 5 healthy subjects and patients with mild (n = 4), moderate (n = 6), and severe (n = 5) chronic obstructive pulmonary disease after 14 days of treatment with 18 μg tiotropium. On day 15, subjects inhaled 2...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Journal of clinical pharmacology 2007-10, Vol.47 (10), p.1335-1341
Hauptverfasser:	Brand, Peter, Meyer, Thomas, Weuthen, Thomas, Timmer, Wolfgang, Berkel, Erhard, Wallenstein, Gudrun, Scheuch, Gerhard
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Inhalation Adult Aged Bronchodilator Agents - administration & dosage Bronchodilator Agents - adverse effects Bronchodilator Agents - pharmacokinetics Complications and side effects COPD Dosage and administration Drug therapy Female Forced Expiratory Volume Handihaler Humans Lung - metabolism Lung - physiopathology lung deposition Lung diseases, Obstructive Male Middle Aged Nebulizers and Vaporizers Physiological aspects Pulmonary Disease, Chronic Obstructive - metabolism Pulmonary Disease, Chronic Obstructive - physiopathology Radiopharmaceuticals Scopolamine Derivatives - administration & dosage Scopolamine Derivatives - adverse effects Scopolamine Derivatives - pharmacokinetics Sodium Pertechnetate Tc 99m Tiotropium Tiotropium Bromide
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!