Mammalian NOTCH-1 Activates beta 1 Integrins via the Small GTPase R-Ras

Notch is a central regulator of important cell fate decisions. Notch activation produces diverse cellular effects suggesting the presence of context-dependent control mechanisms. Genetic studies have demonstrated that Notch and integrin mutations have related phenotypes in key developmental processe...

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Veröffentlicht in:	The Journal of biological chemistry 2007-09, Vol.282 (39), p.28991-29001
Hauptverfasser:	Hodkinson, Philip S, Elliott, PaulA, Lad, Yatish, McHugh, Brian J, MacKinnon, Alison C, Haslett, Christopher, Sethi, Tariq
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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