TRANSFUSION PRACTICE: Antithrombin reduces monocyte and neutrophil CD11b up regulation in addition to blocking platelet activation during extracorporeal circulation

BACKGROUND:Patients undergoing cardiac surgery requiring cardiopulmonary bypass develop a systemic inflammatory reaction. Antithrombin III (AT) has anticoagulant effects but also shows evidence of anti-inflammatory activity. The aim of this study was to examine whether exogenous AT could reduce whit...

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Veröffentlicht in:	Transfusion (Philadelphia, Pa.) Pa.), 2006-07, Vol.46 (7), p.1130-1137
Hauptverfasser:	Rinder, Christine S, Rinder, Henry M, Smith, Michael J, Fitch, Jane CK, Tracey, Jayne B, Chandler, Wayne L, Rollins, Scott A, Smith, Brian R
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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