A Review of Commercial and Medical-Grade Physiological Monitoring Devices for Biofeedback-Assisted Quality of Life Improvement Studies
With the rise in wearable technology and “ health culture ”, we are seeing an increasing interest and affordances in studying how to not only prolong life expectancy but also in how to improve individuals’ quality of life. On the one hand, this attempts to give meaning to the increasing life expecta...
Gespeichert in:
Veröffentlicht in: | Journal of medical systems 2018-06, Vol.42 (6), p.101-10, Article 101 |
---|---|
Hauptverfasser: | , , , , , , , |
Format: | Artikel |
Sprache: | eng |
Schlagworte: | |
Online-Zugang: | Volltext |
Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
container_end_page | 10 |
---|---|
container_issue | 6 |
container_start_page | 101 |
container_title | Journal of medical systems |
container_volume | 42 |
creator | Nogueira, Pedro Urbano, Joana Reis, Luís Paulo Cardoso, Henrique Lopes Silva, Daniel Castro Rocha, Ana Paula Gonçalves, Joaquim Faria, Brígida Mónica |
description | With the rise in wearable technology and “
health culture
”, we are seeing an increasing interest and affordances in studying how to not only prolong life expectancy but also in how to improve individuals’ quality of life. On the one hand, this attempts to give meaning to the increasing life expectancy, as living above a certain threshold of pain and lack of autonomy or mobility is both degrading and unfair. On the other hand, it lowers the cost of continuous care, as individuals with high quality of life indexes tend to have lower hospital readmissions or secondary complications, not to mention higher physical and mental health. In this paper, we evaluate the current state of the art in physiological therapy (biofeedback) along with the existing medical grade and consumer grade hardware for physiological research. We provide a quick primer on the most commonly monitored physiologic metrics, as well as a brief discussion on the current state of the art in biofeedback-assisted medical applications. We then go on to present a comparative analysis between medical and consumer grade biofeedback devices and discuss the hardware specifications and potential practical applications of each consumer grade device in terms of functionality and adaptability for controlled (laboratory) and uncontrolled (field) studies. We end this article with some empirical observations based on our study so that readers might use take them into consideration when arranging a laboratory or real-world experience, thus avoiding costly time delays and material expenditures. |
doi_str_mv | 10.1007/s10916-018-0946-1 |
format | Article |
fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_2027070434</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2026316772</sourcerecordid><originalsourceid>FETCH-LOGICAL-c444t-a8758727e514100858a5b03dd0b681ecc00359878a396ca9d344d17aaa4408cc3</originalsourceid><addsrcrecordid>eNp1kc1u1DAUhS0EokPhAdggS2zYGK4Tx3aWwwCl0lT8S-wsj31TXJJ4aidF8wI8N46mgITE6kpX3zn35xDymMNzDqBeZA4tlwy4ZtAKyfgdsuKNqpnU7de7ZAVcaNY0rT4hD3K-AoBWSnWfnFRLhUqvyM81_Yg3AX_Q2NFNHAZMLtie2tHTC_TB2Z6dJeuRvv92yCH28XLp0Ys4himmMF7SV0XvMNMuJvoyxA7R76z7ztY5hzyhpx9m24fpsEzYhg7p-bBP8QYHHCf6aZp9wPyQ3Otsn_HRbT0lX968_rx5y7bvzs436y1zQoiJWa0arSqFDRflA7rRttlB7T3spOboHEBdzlXa1q10tvW1EJ4ra60QoJ2rT8mzo2_Z4HrGPJkhZId9b0eMczYVVAoUiFoU9Ok_6FWc01i2WyhZc6lUVSh-pFyKOSfszD6FwaaD4WCWkMwxJFNCMktIhhfNk1vneTeg_6P4nUoBqiOQ98uHMf0d_X_XX-JFnIU</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2026316772</pqid></control><display><type>article</type><title>A Review of Commercial and Medical-Grade Physiological Monitoring Devices for Biofeedback-Assisted Quality of Life Improvement Studies</title><source>SpringerLink Journals - AutoHoldings</source><creator>Nogueira, Pedro ; Urbano, Joana ; Reis, Luís Paulo ; Cardoso, Henrique Lopes ; Silva, Daniel Castro ; Rocha, Ana Paula ; Gonçalves, Joaquim ; Faria, Brígida Mónica</creator><creatorcontrib>Nogueira, Pedro ; Urbano, Joana ; Reis, Luís Paulo ; Cardoso, Henrique Lopes ; Silva, Daniel Castro ; Rocha, Ana Paula ; Gonçalves, Joaquim ; Faria, Brígida Mónica</creatorcontrib><description>With the rise in wearable technology and “
health culture
”, we are seeing an increasing interest and affordances in studying how to not only prolong life expectancy but also in how to improve individuals’ quality of life. On the one hand, this attempts to give meaning to the increasing life expectancy, as living above a certain threshold of pain and lack of autonomy or mobility is both degrading and unfair. On the other hand, it lowers the cost of continuous care, as individuals with high quality of life indexes tend to have lower hospital readmissions or secondary complications, not to mention higher physical and mental health. In this paper, we evaluate the current state of the art in physiological therapy (biofeedback) along with the existing medical grade and consumer grade hardware for physiological research. We provide a quick primer on the most commonly monitored physiologic metrics, as well as a brief discussion on the current state of the art in biofeedback-assisted medical applications. We then go on to present a comparative analysis between medical and consumer grade biofeedback devices and discuss the hardware specifications and potential practical applications of each consumer grade device in terms of functionality and adaptability for controlled (laboratory) and uncontrolled (field) studies. We end this article with some empirical observations based on our study so that readers might use take them into consideration when arranging a laboratory or real-world experience, thus avoiding costly time delays and material expenditures.</description><identifier>ISSN: 0148-5598</identifier><identifier>EISSN: 1573-689X</identifier><identifier>DOI: 10.1007/s10916-018-0946-1</identifier><identifier>PMID: 29667028</identifier><language>eng</language><publisher>New York: Springer US</publisher><subject>Adaptability ; Autonomy ; Biofeedback ; Comparative analysis ; Complications ; Empirical analysis ; Feedback ; Health Informatics ; Health Information Systems & Technologies ; Health Sciences ; Life assessment ; Literature reviews ; Medical electronics ; Medical research ; Medicine ; Medicine & Public Health ; Mental health ; Mobile & Wireless Health ; Pain ; Physiology ; Quality of life ; Statistics for Life Sciences</subject><ispartof>Journal of medical systems, 2018-06, Vol.42 (6), p.101-10, Article 101</ispartof><rights>Springer Science+Business Media, LLC, part of Springer Nature 2018</rights><rights>Journal of Medical Systems is a copyright of Springer, (2018). All Rights Reserved.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c444t-a8758727e514100858a5b03dd0b681ecc00359878a396ca9d344d17aaa4408cc3</citedby><cites>FETCH-LOGICAL-c444t-a8758727e514100858a5b03dd0b681ecc00359878a396ca9d344d17aaa4408cc3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s10916-018-0946-1$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s10916-018-0946-1$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,780,784,27924,27925,41488,42557,51319</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/29667028$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Nogueira, Pedro</creatorcontrib><creatorcontrib>Urbano, Joana</creatorcontrib><creatorcontrib>Reis, Luís Paulo</creatorcontrib><creatorcontrib>Cardoso, Henrique Lopes</creatorcontrib><creatorcontrib>Silva, Daniel Castro</creatorcontrib><creatorcontrib>Rocha, Ana Paula</creatorcontrib><creatorcontrib>Gonçalves, Joaquim</creatorcontrib><creatorcontrib>Faria, Brígida Mónica</creatorcontrib><title>A Review of Commercial and Medical-Grade Physiological Monitoring Devices for Biofeedback-Assisted Quality of Life Improvement Studies</title><title>Journal of medical systems</title><addtitle>J Med Syst</addtitle><addtitle>J Med Syst</addtitle><description>With the rise in wearable technology and “
health culture
”, we are seeing an increasing interest and affordances in studying how to not only prolong life expectancy but also in how to improve individuals’ quality of life. On the one hand, this attempts to give meaning to the increasing life expectancy, as living above a certain threshold of pain and lack of autonomy or mobility is both degrading and unfair. On the other hand, it lowers the cost of continuous care, as individuals with high quality of life indexes tend to have lower hospital readmissions or secondary complications, not to mention higher physical and mental health. In this paper, we evaluate the current state of the art in physiological therapy (biofeedback) along with the existing medical grade and consumer grade hardware for physiological research. We provide a quick primer on the most commonly monitored physiologic metrics, as well as a brief discussion on the current state of the art in biofeedback-assisted medical applications. We then go on to present a comparative analysis between medical and consumer grade biofeedback devices and discuss the hardware specifications and potential practical applications of each consumer grade device in terms of functionality and adaptability for controlled (laboratory) and uncontrolled (field) studies. We end this article with some empirical observations based on our study so that readers might use take them into consideration when arranging a laboratory or real-world experience, thus avoiding costly time delays and material expenditures.</description><subject>Adaptability</subject><subject>Autonomy</subject><subject>Biofeedback</subject><subject>Comparative analysis</subject><subject>Complications</subject><subject>Empirical analysis</subject><subject>Feedback</subject><subject>Health Informatics</subject><subject>Health Information Systems & Technologies</subject><subject>Health Sciences</subject><subject>Life assessment</subject><subject>Literature reviews</subject><subject>Medical electronics</subject><subject>Medical research</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Mental health</subject><subject>Mobile & Wireless Health</subject><subject>Pain</subject><subject>Physiology</subject><subject>Quality of life</subject><subject>Statistics for Life Sciences</subject><issn>0148-5598</issn><issn>1573-689X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2018</creationdate><recordtype>article</recordtype><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><recordid>eNp1kc1u1DAUhS0EokPhAdggS2zYGK4Tx3aWwwCl0lT8S-wsj31TXJJ4aidF8wI8N46mgITE6kpX3zn35xDymMNzDqBeZA4tlwy4ZtAKyfgdsuKNqpnU7de7ZAVcaNY0rT4hD3K-AoBWSnWfnFRLhUqvyM81_Yg3AX_Q2NFNHAZMLtie2tHTC_TB2Z6dJeuRvv92yCH28XLp0Ys4himmMF7SV0XvMNMuJvoyxA7R76z7ztY5hzyhpx9m24fpsEzYhg7p-bBP8QYHHCf6aZp9wPyQ3Otsn_HRbT0lX968_rx5y7bvzs436y1zQoiJWa0arSqFDRflA7rRttlB7T3spOboHEBdzlXa1q10tvW1EJ4ra60QoJ2rT8mzo2_Z4HrGPJkhZId9b0eMczYVVAoUiFoU9Ok_6FWc01i2WyhZc6lUVSh-pFyKOSfszD6FwaaD4WCWkMwxJFNCMktIhhfNk1vneTeg_6P4nUoBqiOQ98uHMf0d_X_XX-JFnIU</recordid><startdate>20180601</startdate><enddate>20180601</enddate><creator>Nogueira, Pedro</creator><creator>Urbano, Joana</creator><creator>Reis, Luís Paulo</creator><creator>Cardoso, Henrique Lopes</creator><creator>Silva, Daniel Castro</creator><creator>Rocha, Ana Paula</creator><creator>Gonçalves, Joaquim</creator><creator>Faria, Brígida Mónica</creator><general>Springer US</general><general>Springer Nature B.V</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7QF</scope><scope>7QO</scope><scope>7QQ</scope><scope>7RV</scope><scope>7SC</scope><scope>7SE</scope><scope>7SP</scope><scope>7SR</scope><scope>7TA</scope><scope>7TB</scope><scope>7TK</scope><scope>7U5</scope><scope>7X7</scope><scope>7XB</scope><scope>88C</scope><scope>88E</scope><scope>88I</scope><scope>8AL</scope><scope>8AO</scope><scope>8BQ</scope><scope>8FD</scope><scope>8FE</scope><scope>8FG</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>ARAPS</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BGLVJ</scope><scope>BHPHI</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>F28</scope><scope>FR3</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>H8D</scope><scope>H8G</scope><scope>HCIFZ</scope><scope>JG9</scope><scope>JQ2</scope><scope>K7-</scope><scope>K9.</scope><scope>KB0</scope><scope>KR7</scope><scope>L7M</scope><scope>LK8</scope><scope>L~C</scope><scope>L~D</scope><scope>M0N</scope><scope>M0S</scope><scope>M0T</scope><scope>M1P</scope><scope>M2P</scope><scope>M7P</scope><scope>NAPCQ</scope><scope>P5Z</scope><scope>P62</scope><scope>P64</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>Q9U</scope><scope>7X8</scope></search><sort><creationdate>20180601</creationdate><title>A Review of Commercial and Medical-Grade Physiological Monitoring Devices for Biofeedback-Assisted Quality of Life Improvement Studies</title><author>Nogueira, Pedro ; Urbano, Joana ; Reis, Luís Paulo ; Cardoso, Henrique Lopes ; Silva, Daniel Castro ; Rocha, Ana Paula ; Gonçalves, Joaquim ; Faria, Brígida Mónica</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c444t-a8758727e514100858a5b03dd0b681ecc00359878a396ca9d344d17aaa4408cc3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2018</creationdate><topic>Adaptability</topic><topic>Autonomy</topic><topic>Biofeedback</topic><topic>Comparative analysis</topic><topic>Complications</topic><topic>Empirical analysis</topic><topic>Feedback</topic><topic>Health Informatics</topic><topic>Health Information Systems & Technologies</topic><topic>Health Sciences</topic><topic>Life assessment</topic><topic>Literature reviews</topic><topic>Medical electronics</topic><topic>Medical research</topic><topic>Medicine</topic><topic>Medicine & Public Health</topic><topic>Mental health</topic><topic>Mobile & Wireless Health</topic><topic>Pain</topic><topic>Physiology</topic><topic>Quality of life</topic><topic>Statistics for Life Sciences</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Nogueira, Pedro</creatorcontrib><creatorcontrib>Urbano, Joana</creatorcontrib><creatorcontrib>Reis, Luís Paulo</creatorcontrib><creatorcontrib>Cardoso, Henrique Lopes</creatorcontrib><creatorcontrib>Silva, Daniel Castro</creatorcontrib><creatorcontrib>Rocha, Ana Paula</creatorcontrib><creatorcontrib>Gonçalves, Joaquim</creatorcontrib><creatorcontrib>Faria, Brígida Mónica</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Aluminium Industry Abstracts</collection><collection>Biotechnology Research Abstracts</collection><collection>Ceramic Abstracts</collection><collection>Proquest Nursing & Allied Health Source</collection><collection>Computer and Information Systems Abstracts</collection><collection>Corrosion Abstracts</collection><collection>Electronics & Communications Abstracts</collection><collection>Engineered Materials Abstracts</collection><collection>Materials Business File</collection><collection>Mechanical & Transportation Engineering Abstracts</collection><collection>Neurosciences Abstracts</collection><collection>Solid State and Superconductivity Abstracts</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Healthcare Administration Database (Alumni)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Science Database (Alumni Edition)</collection><collection>Computing Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>METADEX</collection><collection>Technology Research Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Technology Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>Advanced Technologies & Aerospace Collection</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Technology Collection</collection><collection>Natural Science Collection</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>ANTE: Abstracts in New Technology & Engineering</collection><collection>Engineering Research Database</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>Aerospace Database</collection><collection>Copper Technical Reference Library</collection><collection>SciTech Premium Collection</collection><collection>Materials Research Database</collection><collection>ProQuest Computer Science Collection</collection><collection>Computer Science Database</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>Civil Engineering Abstracts</collection><collection>Advanced Technologies Database with Aerospace</collection><collection>ProQuest Biological Science Collection</collection><collection>Computer and Information Systems Abstracts Academic</collection><collection>Computer and Information Systems Abstracts Professional</collection><collection>Computing Database</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Healthcare Administration Database</collection><collection>Medical Database</collection><collection>Science Database</collection><collection>Biological Science Database</collection><collection>Nursing & Allied Health Premium</collection><collection>Advanced Technologies & Aerospace Database</collection><collection>ProQuest Advanced Technologies & Aerospace Collection</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of medical systems</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Nogueira, Pedro</au><au>Urbano, Joana</au><au>Reis, Luís Paulo</au><au>Cardoso, Henrique Lopes</au><au>Silva, Daniel Castro</au><au>Rocha, Ana Paula</au><au>Gonçalves, Joaquim</au><au>Faria, Brígida Mónica</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>A Review of Commercial and Medical-Grade Physiological Monitoring Devices for Biofeedback-Assisted Quality of Life Improvement Studies</atitle><jtitle>Journal of medical systems</jtitle><stitle>J Med Syst</stitle><addtitle>J Med Syst</addtitle><date>2018-06-01</date><risdate>2018</risdate><volume>42</volume><issue>6</issue><spage>101</spage><epage>10</epage><pages>101-10</pages><artnum>101</artnum><issn>0148-5598</issn><eissn>1573-689X</eissn><abstract>With the rise in wearable technology and “
health culture
”, we are seeing an increasing interest and affordances in studying how to not only prolong life expectancy but also in how to improve individuals’ quality of life. On the one hand, this attempts to give meaning to the increasing life expectancy, as living above a certain threshold of pain and lack of autonomy or mobility is both degrading and unfair. On the other hand, it lowers the cost of continuous care, as individuals with high quality of life indexes tend to have lower hospital readmissions or secondary complications, not to mention higher physical and mental health. In this paper, we evaluate the current state of the art in physiological therapy (biofeedback) along with the existing medical grade and consumer grade hardware for physiological research. We provide a quick primer on the most commonly monitored physiologic metrics, as well as a brief discussion on the current state of the art in biofeedback-assisted medical applications. We then go on to present a comparative analysis between medical and consumer grade biofeedback devices and discuss the hardware specifications and potential practical applications of each consumer grade device in terms of functionality and adaptability for controlled (laboratory) and uncontrolled (field) studies. We end this article with some empirical observations based on our study so that readers might use take them into consideration when arranging a laboratory or real-world experience, thus avoiding costly time delays and material expenditures.</abstract><cop>New York</cop><pub>Springer US</pub><pmid>29667028</pmid><doi>10.1007/s10916-018-0946-1</doi><tpages>10</tpages><oa>free_for_read</oa></addata></record> |
fulltext | fulltext |
identifier | ISSN: 0148-5598 |
ispartof | Journal of medical systems, 2018-06, Vol.42 (6), p.101-10, Article 101 |
issn | 0148-5598 1573-689X |
language | eng |
recordid | cdi_proquest_miscellaneous_2027070434 |
source | SpringerLink Journals - AutoHoldings |
subjects | Adaptability Autonomy Biofeedback Comparative analysis Complications Empirical analysis Feedback Health Informatics Health Information Systems & Technologies Health Sciences Life assessment Literature reviews Medical electronics Medical research Medicine Medicine & Public Health Mental health Mobile & Wireless Health Pain Physiology Quality of life Statistics for Life Sciences |
title | A Review of Commercial and Medical-Grade Physiological Monitoring Devices for Biofeedback-Assisted Quality of Life Improvement Studies |
url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-06T22%3A54%3A35IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=A%20Review%20of%20Commercial%20and%20Medical-Grade%20Physiological%20Monitoring%20Devices%20for%20Biofeedback-Assisted%20Quality%20of%20Life%20Improvement%20Studies&rft.jtitle=Journal%20of%20medical%20systems&rft.au=Nogueira,%20Pedro&rft.date=2018-06-01&rft.volume=42&rft.issue=6&rft.spage=101&rft.epage=10&rft.pages=101-10&rft.artnum=101&rft.issn=0148-5598&rft.eissn=1573-689X&rft_id=info:doi/10.1007/s10916-018-0946-1&rft_dat=%3Cproquest_cross%3E2026316772%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2026316772&rft_id=info:pmid/29667028&rfr_iscdi=true |