Hyperbaric oxygen-induced attenuation of hemorrhagic transformation after experimental focal transient cerebral ischemia

An increased risk of hemorrhagic transformation is a major factor limiting the use of tissue plasminogen activator for stroke. Increased hemorrhagic transformation is also found in animals undergoing transient focal cerebral ischemia with hyperglycemia; this study examined whether hyperbaric oxygen...

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Veröffentlicht in:	Stroke (1970) 2007-04, Vol.38 (4), p.1362-1367
Hauptverfasser:	ZHIYONG QIN, KARABIYIKOGLU, Murat, YA HUA, SILBERGLEIT, Robert, YANGDONG HE, KEEP, Richard F, GUOHUA XI
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Blood-Brain Barrier - drug effects Blood-Brain Barrier - physiopathology Cerebral circulation. Blood-brain barrier. Choroid plexus. Cerebrospinal fluid. Circumventricular organ. Meninges Cerebral Hemorrhage - etiology Cerebral Hemorrhage - physiopathology Cerebral Hemorrhage - prevention & control Cerebral Infarction - complications Cerebral Infarction - physiopathology Disease Models, Animal Fibrinolytic Agents - adverse effects Fundamental and applied biological sciences. Psychology Hemoglobins - metabolism Hyperbaric Oxygenation - methods Infarction, Middle Cerebral Artery - complications Infarction, Middle Cerebral Artery - physiopathology Ischemic Attack, Transient - complications Ischemic Attack, Transient - physiopathology Male Medical sciences Neurology Neuropharmacology Neuroprotective agent Oxygen - pharmacology Oxygen - therapeutic use Pharmacology. Drug treatments Rats Rats, Sprague-Dawley Reperfusion Injury - complications Reperfusion Injury - physiopathology Tissue Plasminogen Activator - adverse effects Treatment Outcome Vascular diseases and vascular malformations of the nervous system Vertebrates: nervous system and sense organs
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