Worsening of osteonecrosis of the jaw during treatment with sunitinib in a patient with metastatic renal cell carcinoma

Abstract We report on the potential association of suspected bisphosphonate-associated osteonecrosis of the jaw (BRONJ) recurrence with the use of the novel antiangiogenic drug sunitinib. A 59 year-old patient affected by metastatic renal cell carcinoma (RCC) and established BRONJ experienced consec...

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Veröffentlicht in:	Bone (New York, N.Y.) N.Y.), 2009-01, Vol.44 (1), p.173-175
Hauptverfasser:	Brunello, Antonella, Saia, Giorgia, Bedogni, Alberto, Scaglione, Daniela, Basso, Umberto
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Bisphosphonates Carcinoma, Renal Cell - complications Carcinoma, Renal Cell - drug therapy Carcinoma, Renal Cell - pathology Dental Fistula - chemically induced Dental Fistula - complications Diseases of the osteoarticular system Fundamental and applied biological sciences. Psychology Humans Indoles - adverse effects Indoles - therapeutic use Jaw Diseases - chemically induced Jaw Diseases - complications Kidney Neoplasms - complications Kidney Neoplasms - drug therapy Kidney Neoplasms - pathology Kidneys Lung Neoplasms - complications Lung Neoplasms - secondary Male Medical sciences Metastatic renal cell carcinoma Middle Aged Nephrology. Urinary tract diseases Orthopedics Osteonecrosis - chemically induced Osteonecrosis - complications Osteonecrosis of the jaw Pyrroles - adverse effects Pyrroles - therapeutic use Sunitinib Tumors of the urinary system Tyrosine kinase inhibitors Vascular bone diseases Vertebrates: anatomy and physiology, studies on body, several organs or systems
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