Does intranasal dexmedetomidine provide adequate plasma concentrations for sedation in children: a pharmacokinetic study

Atomised intranasal dexmedetomidine administration is an attractive option when sedation is required for paediatric diagnostic procedures, as vascular access is not required. The risk of haemodynamic instability caused by dexmedetomidine necessitates better understanding of its pharmacokinetics in y...

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Veröffentlicht in:	British journal of anaesthesia : BJA 2018-05, Vol.120 (5), p.1056-1065
Hauptverfasser:	Miller, J.W., Balyan, R., Dong, M., Mahmoud, M., Lam, J.E., Pratap, J.N., Paquin, J.R., Li, B.L., Spaeth, J.P., Vinks, A., Loepke, A.W.
Format:	Artikel
Sprache:	eng
Schlagworte:	anaesthesia dexmedetomidine intranasal paediatrics pharmacokinetics
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