Nicotine induces DNA damage in human salivary glands

The tobacco alkaloid nicotine is responsible for addiction to tobacco and supposed to contribute to tobacco carcinogensis, too. Recently, genotoxic effects of nicotine have been reported in human cells from blood and upper aerodigestive tract. Because of nicotine accumulation in saliva, the study of...

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Veröffentlicht in:	Toxicology letters 2009-01, Vol.184 (1), p.1-4
Hauptverfasser:	Ginzkey, Christian, Kampfinger, Katja, Friehs, Gudrun, Köhler, Christian, Hagen, Rudolf, Richter, Elmar, Kleinsasser, Norbert H.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aged, 80 and over Biological and medical sciences Cells, Cultured Comet assay Comet Assay - methods DNA Damage Female Genotoxicity Humans In Vitro Techniques Male Medical sciences Middle Aged Mutagenicity Tests Nicotine Nicotine - adverse effects Nicotinic Agonists - adverse effects Parotid gland Parotid Gland - drug effects Smoking - adverse effects Tobacco, tobacco smoking Toxicology
Online-Zugang:	Volltext
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