Polygonum aviculare L. extract reduces fatigue by inhibiting neuroinflammation in restraint-stressed mice

Chronic fatigue patients experience various neuropsychological symptoms, including fatigue behaviors, chronic pain, and depression. They also display immune system dysregulation. Polygonum aviculare L. extract (PAE) is a traditional herbal medicine used to treat inflammatory diseases by reportedly d...

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Veröffentlicht in:	Phytomedicine (Stuttgart) 2018-03, Vol.42, p.180-189
Hauptverfasser:	Park, Sun Haeng, Jang, Seol, Son, Eunjung, Lee, Si Woo, Park, Sun Dong, Sung, Yoon-Young, Kim, Ho Kyoung
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Anti-Inflammatory Agents, Non-Steroidal - chemistry Anti-Inflammatory Agents, Non-Steroidal - pharmacology Brain - drug effects Brain - metabolism Brain - pathology Corticosterone - blood Cytokines - metabolism Disease Models, Animal Drugs, Chinese Herbal - pharmacology Fatigue Fatigue - drug therapy Fatigue - physiopathology Flavonoids - analysis Inflammation - drug therapy Male Mibyeong Mice, Inbred C57BL Plant Extracts - pharmacology Polygonum - chemistry Polygonum aviculare L Restraint stress Serotonin - metabolism Stress Stress, Physiological - drug effects
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