Investigation of the therapy targets of Yi-Qi-Yang-Yin-Hua-Tan-Qu-Yu recipe on type 2 diabetes by serum proteome labeled with iTRAQ

Based on basic theories of Chinese medicine, Yi-Qi-Yang-Yin-Hua-Tan-Qu-Yu (YQYYHTQY) recipe was constituted by eleven kinds of Chinese herbs and effective in treatment of type 2 diabetes (T2DM). But the therapy target was unclear. In this study, we used the serum proteome labeled by iTRAQ to find th...

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Veröffentlicht in:	Journal of ethnopharmacology 2018-10, Vol.224 (NA), p.1-14
Hauptverfasser:	Zhao, Jing, Cai, Cheng-Ke, Xie, Ming, Liu, Jin-Na, Wang, Bang-Zhong
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Behavior, Animal - drug effects Blood Proteins - analysis CDC42 Chinese herb formula Diabetes Mellitus, Experimental - blood Diabetes Mellitus, Experimental - drug therapy Diabetes Mellitus, Type 2 - blood Diabetes Mellitus, Type 2 - drug therapy Drugs, Chinese Herbal - pharmacology Drugs, Chinese Herbal - therapeutic use Hypoglycemic Agents - pharmacology Hypoglycemic Agents - therapeutic use Male Proteome Proteomics Rats, Sprague-Dawley RhoA Serum proteome Type 2 diabetes
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