The use of molecular descriptors in the development of co-amorphous formulations

Co-amorphous systems consisting of a drug and an amino acid have been investigated extensively for the enhancement of drug solubility and amorphous stability. The purpose of this study is to investigate which molecular descriptors are important for predicting the likelihood of a successful co-amorph...

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Veröffentlicht in:	European journal of pharmaceutical sciences 2018-07, Vol.119, p.31-38
Hauptverfasser:	Meng-Lund, Helena, Kasten, Georgia, Jensen, Katrine Tarp, Poso, Antti, Pantsar, Tatu, Rades, Thomas, Rantanen, Jukka, Grohganz, Holger
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino acids Co-amorphous Molecular descriptors Multivariate data analysis PLS-DA
Online-Zugang:	Volltext
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