Design of Mannose-Functionalized Curdlan Nanoparticles for Macrophage-Targeted siRNA Delivery

6-Amino-6-deoxy-curdlan is a promising nucleic acid carrier that efficiently delivers plasmid DNA as well as short interfering RNA (siRNA) to various cell lines. The highly reactive C6-NH2 groups of 6-amino-6-deoxy-curdlan prompt conjugation of various side groups including tissue-targeting ligands...

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Veröffentlicht in:	ACS applied materials & interfaces 2018-05, Vol.10 (17), p.14463-14474
Hauptverfasser:	Ganbold, Tsogzolmaa, Baigude, Huricha
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals beta-Glucans Macrophages Mannose Mice Nanoparticles RNA, Small Interfering
Online-Zugang:	Volltext
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