Profile and Content of Betalains in Plasma and Urine of Volunteers after Long-Term Exposure to Fermented Red Beet Juice

Profile and Content of Betalains in Plasma and Urine of Volunteers after Long-Term Exposure to Fermented Red Beet Juice

The aim of this study was to determine profile and content of betalains in volunteers’ plasma and urine after long-term exposure to fermented red beet juice. During 6 weeks, 24 healthy volunteers consumed juice with a dose of 0.7 mg betalains/kg body weight. Betalains were analyzed by means of micro...

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Veröffentlicht in:Journal of agricultural and food chemistry 2018-04, Vol.66 (16), p.4155-4163
Hauptverfasser: Sawicki, Tomasz, Topolska, Joanna, Romaszko, Ewa, Wiczkowski, Wiesław
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container_end_page 4163
container_issue 16
container_start_page 4155
container_title Journal of agricultural and food chemistry
container_volume 66
creator Sawicki, Tomasz
Topolska, Joanna
Romaszko, Ewa
Wiczkowski, Wiesław
description The aim of this study was to determine profile and content of betalains in volunteers’ plasma and urine after long-term exposure to fermented red beet juice. During 6 weeks, 24 healthy volunteers consumed juice with a dose of 0.7 mg betalains/kg body weight. Betalains were analyzed by means of micro-HPLC-MS/MS. Twelve betalain derivatives were found in blood plasma and urine after juice intake. The highest betalains level in blood plasma (87.65 ± 15.71 nmol/L) and urine (1.14 ± 0.12 μmol) was found after the first and second week of juice intake, respectively. During juice consumption, the contribution of betalain metabolites was higher than that of native betalains, and interindividual variability in profile and content of betalains was observed. Summarizing, it was observed that long-term and regular consumption of the juice causes stabilization of profile and content of betalains in physiological fluids of volunteers, which include native compounds and their decarboxylated and dehydrogenated metabolites.
doi_str_mv 10.1021/acs.jafc.8b00925
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title Profile and Content of Betalains in Plasma and Urine of Volunteers after Long-Term Exposure to Fermented Red Beet Juice
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