Effects of replacing diet beverages with water on weight loss and weight maintenance: 18-month follow-up, randomized clinical trial

Background: Beneficial effects of replacing diet beverages (DBs) with water on weight loss, during a 24-week hypoenergetic diet were previously observed. However, it is not known whether this difference is sustained during a subsequent 12-month weight maintenance period. Objective: To evaluate effec...

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Veröffentlicht in:International Journal of Obesity 2018-04, Vol.42 (4), p.835-840
Hauptverfasser: Madjd, A, Taylor, M A, Delavari, A, Malekzadeh, R, Macdonald, I A, Farshchi, H R
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container_issue 4
container_start_page 835
container_title International Journal of Obesity
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creator Madjd, A
Taylor, M A
Delavari, A
Malekzadeh, R
Macdonald, I A
Farshchi, H R
description Background: Beneficial effects of replacing diet beverages (DBs) with water on weight loss, during a 24-week hypoenergetic diet were previously observed. However, it is not known whether this difference is sustained during a subsequent 12-month weight maintenance period. Objective: To evaluate effects of replacing DBs with water on body weight maintenance over a 12-month period in participants who undertook a 6-month weight loss plan. Design: Seventy-one obese and overweight adult women (body mass index (BMI): 27–40 kg m –2 ; age: 18–50 years) who usually consumed DBs in their diet were randomly assigned to either substitute water for DBs (water group: 35) or continue drinking DBs five times per week (DBs group: 36) after their lunch for the 6-month weight loss intervention and subsequent 12-month weight maintenance program. Results: A total of 71 participants who were randomly assigned were included in the study by using an intention-to-treat analysis. Greater additional weight loss (mean±s.d.) in the water group was observed compared with the DBs group after the 12-month follow-up period (−1.7±2.8 vs −0.1±2.7 kg, P =0.001). BMI decreased more in the water group than in the DBs group (−0.7±1 vs −0.05±1.1 kg m – 2 , P =0.003). There was also a greater reduction in fasting insulin levels (−0.5±1.4 vs −0.02±1.5 mmol l –1 , P =0.023), better improvement in homeostasis model assessment of insulin resistance (−0.2±0.4 vs −0.1±0.3, P =0.013) and a greater decrease in 2-h postprandial plasma glucose (−0.2±0.3 vs −0.1±0.3 mmol l –1 , P
doi_str_mv 10.1038/ijo.2017.306
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However, it is not known whether this difference is sustained during a subsequent 12-month weight maintenance period. Objective: To evaluate effects of replacing DBs with water on body weight maintenance over a 12-month period in participants who undertook a 6-month weight loss plan. Design: Seventy-one obese and overweight adult women (body mass index (BMI): 27–40 kg m –2 ; age: 18–50 years) who usually consumed DBs in their diet were randomly assigned to either substitute water for DBs (water group: 35) or continue drinking DBs five times per week (DBs group: 36) after their lunch for the 6-month weight loss intervention and subsequent 12-month weight maintenance program. Results: A total of 71 participants who were randomly assigned were included in the study by using an intention-to-treat analysis. Greater additional weight loss (mean±s.d.) in the water group was observed compared with the DBs group after the 12-month follow-up period (−1.7±2.8 vs −0.1±2.7 kg, P =0.001). BMI decreased more in the water group than in the DBs group (−0.7±1 vs −0.05±1.1 kg m – 2 , P =0.003). There was also a greater reduction in fasting insulin levels (−0.5±1.4 vs −0.02±1.5 mmol l –1 , P =0.023), better improvement in homeostasis model assessment of insulin resistance (−0.2±0.4 vs −0.1±0.3, P =0.013) and a greater decrease in 2-h postprandial plasma glucose (−0.2±0.3 vs −0.1±0.3 mmol l –1 , P &lt;0.001) in the water group compared with the DBs over the 12-month weight maintenance period. Conclusions: Replacement of DBs with water after the main meal in women who were regular users of DBs may cause further weight reduction during a 12-month weight maintenance program. It may also offer benefits in carbohydrate metabolism including improvement of insulin resistance over the long-term weight maintenance period.</description><identifier>ISSN: 0307-0565</identifier><identifier>EISSN: 1476-5497</identifier><identifier>DOI: 10.1038/ijo.2017.306</identifier><identifier>PMID: 29633983</identifier><language>eng</language><publisher>London: Nature Publishing Group UK</publisher><subject>631/443/319/1557 ; 692/163/2743/393 ; Beverages ; Body mass index ; Body size ; Body weight ; Body weight loss ; Carbohydrate metabolism ; Carbohydrates ; Clinical trials ; Diet ; Diet soft drinks ; Drinking water ; Epidemiology ; Fads ; Health aspects ; Health Promotion and Disease Prevention ; Homeostasis ; Influence ; Insulin ; Insulin resistance ; Internal Medicine ; Maintenance ; Medicine ; Medicine &amp; Public Health ; Metabolic Diseases ; Metabolism ; Motivation ; original-article ; Overweight ; Public Health ; Weight loss ; Weight reduction ; Women</subject><ispartof>International Journal of Obesity, 2018-04, Vol.42 (4), p.835-840</ispartof><rights>Macmillan Publishers Limited, part of Springer Nature. 2018</rights><rights>COPYRIGHT 2018 Nature Publishing Group</rights><rights>Copyright Nature Publishing Group Apr 2018</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c455t-9088645835fac9283d2c2ee51c7f3e0f540958a6867f8cb01ee58479af618bb33</citedby><cites>FETCH-LOGICAL-c455t-9088645835fac9283d2c2ee51c7f3e0f540958a6867f8cb01ee58479af618bb33</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1038/ijo.2017.306$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1038/ijo.2017.306$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,776,780,27901,27902,41464,42533,51294</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/29633983$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Madjd, A</creatorcontrib><creatorcontrib>Taylor, M A</creatorcontrib><creatorcontrib>Delavari, A</creatorcontrib><creatorcontrib>Malekzadeh, R</creatorcontrib><creatorcontrib>Macdonald, I A</creatorcontrib><creatorcontrib>Farshchi, H R</creatorcontrib><title>Effects of replacing diet beverages with water on weight loss and weight maintenance: 18-month follow-up, randomized clinical trial</title><title>International Journal of Obesity</title><addtitle>Int J Obes</addtitle><addtitle>Int J Obes (Lond)</addtitle><description>Background: Beneficial effects of replacing diet beverages (DBs) with water on weight loss, during a 24-week hypoenergetic diet were previously observed. However, it is not known whether this difference is sustained during a subsequent 12-month weight maintenance period. Objective: To evaluate effects of replacing DBs with water on body weight maintenance over a 12-month period in participants who undertook a 6-month weight loss plan. Design: Seventy-one obese and overweight adult women (body mass index (BMI): 27–40 kg m –2 ; age: 18–50 years) who usually consumed DBs in their diet were randomly assigned to either substitute water for DBs (water group: 35) or continue drinking DBs five times per week (DBs group: 36) after their lunch for the 6-month weight loss intervention and subsequent 12-month weight maintenance program. Results: A total of 71 participants who were randomly assigned were included in the study by using an intention-to-treat analysis. Greater additional weight loss (mean±s.d.) in the water group was observed compared with the DBs group after the 12-month follow-up period (−1.7±2.8 vs −0.1±2.7 kg, P =0.001). BMI decreased more in the water group than in the DBs group (−0.7±1 vs −0.05±1.1 kg m – 2 , P =0.003). There was also a greater reduction in fasting insulin levels (−0.5±1.4 vs −0.02±1.5 mmol l –1 , P =0.023), better improvement in homeostasis model assessment of insulin resistance (−0.2±0.4 vs −0.1±0.3, P =0.013) and a greater decrease in 2-h postprandial plasma glucose (−0.2±0.3 vs −0.1±0.3 mmol l –1 , P &lt;0.001) in the water group compared with the DBs over the 12-month weight maintenance period. Conclusions: Replacement of DBs with water after the main meal in women who were regular users of DBs may cause further weight reduction during a 12-month weight maintenance program. 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However, it is not known whether this difference is sustained during a subsequent 12-month weight maintenance period. Objective: To evaluate effects of replacing DBs with water on body weight maintenance over a 12-month period in participants who undertook a 6-month weight loss plan. Design: Seventy-one obese and overweight adult women (body mass index (BMI): 27–40 kg m –2 ; age: 18–50 years) who usually consumed DBs in their diet were randomly assigned to either substitute water for DBs (water group: 35) or continue drinking DBs five times per week (DBs group: 36) after their lunch for the 6-month weight loss intervention and subsequent 12-month weight maintenance program. Results: A total of 71 participants who were randomly assigned were included in the study by using an intention-to-treat analysis. Greater additional weight loss (mean±s.d.) in the water group was observed compared with the DBs group after the 12-month follow-up period (−1.7±2.8 vs −0.1±2.7 kg, P =0.001). BMI decreased more in the water group than in the DBs group (−0.7±1 vs −0.05±1.1 kg m – 2 , P =0.003). There was also a greater reduction in fasting insulin levels (−0.5±1.4 vs −0.02±1.5 mmol l –1 , P =0.023), better improvement in homeostasis model assessment of insulin resistance (−0.2±0.4 vs −0.1±0.3, P =0.013) and a greater decrease in 2-h postprandial plasma glucose (−0.2±0.3 vs −0.1±0.3 mmol l –1 , P &lt;0.001) in the water group compared with the DBs over the 12-month weight maintenance period. Conclusions: Replacement of DBs with water after the main meal in women who were regular users of DBs may cause further weight reduction during a 12-month weight maintenance program. It may also offer benefits in carbohydrate metabolism including improvement of insulin resistance over the long-term weight maintenance period.</abstract><cop>London</cop><pub>Nature Publishing Group UK</pub><pmid>29633983</pmid><doi>10.1038/ijo.2017.306</doi><tpages>6</tpages></addata></record>
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source Springer Nature - Connect here FIRST to enable access; SpringerLink Journals - AutoHoldings
subjects 631/443/319/1557
692/163/2743/393
Beverages
Body mass index
Body size
Body weight
Body weight loss
Carbohydrate metabolism
Carbohydrates
Clinical trials
Diet
Diet soft drinks
Drinking water
Epidemiology
Fads
Health aspects
Health Promotion and Disease Prevention
Homeostasis
Influence
Insulin
Insulin resistance
Internal Medicine
Maintenance
Medicine
Medicine & Public Health
Metabolic Diseases
Metabolism
Motivation
original-article
Overweight
Public Health
Weight loss
Weight reduction
Women
title Effects of replacing diet beverages with water on weight loss and weight maintenance: 18-month follow-up, randomized clinical trial
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