Effects of hypoxia inducible factors on pluripotency in human iPS cells

A hypoxic condition is known to contribute to pluripotency. In the present article, the effects of transcription factors were first assessed regarding the proliferation and differentiation of human induced pluripotent stem (iPS) cells under hypoxic conditions using cell morphology and real‐time poly...

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Veröffentlicht in:	Microscopy research and technique 2018-07, Vol.81 (7), p.749-754
Hauptverfasser:	Sugimoto, Kouji, Matsuura, Takashi, Nakazono, Ayako, Igawa, Kazunari, Yamada, Shizuka, Hayashi, Yoshihiko, Diaspro, Alberto
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Basic Helix-Loop-Helix Transcription Factors - genetics Basic Helix-Loop-Helix Transcription Factors - metabolism Cell Differentiation Cell Hypoxia Cell morphology Cell Proliferation Colonies Cyclic S-Oxides - pharmacology Cytology Gene Expression Regulation - drug effects Humans Hypoxia hypoxic condition Induced Pluripotent Stem Cells - cytology Induced Pluripotent Stem Cells - drug effects Markers Mice Morphology Pluripotency pluripotency marker Polymerase chain reaction Real-Time Polymerase Chain Reaction Reduction RNA, Small Interfering Signal Transduction siRNA STAT3 Stat3 protein STAT3 Transcription Factor - antagonists & inhibitors STAT3 Transcription Factor - genetics Statistical analysis Transcription factors
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