CAPSAICIN: ITS BIOLOGICAL ACTIVITIES AND IN SILICO TARGET FISHING
Capsicum annuum L. is a rich source of capsaicin, an alkaloid, which is a very pungent compound. Due to ever growing need of capsaicin, an extensive research on its efficient cultivation as well as chemical synthesis is underway. Owing to the pungent nature of capsaicin, its analogous molecules with...
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| Veröffentlicht in: | Acta Poloniae pharmaceutica 2017-03, Vol.74 (2), p.321-329 |
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| container_title | Acta Poloniae pharmaceutica |
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| creator | Akhtar, Fahad Muhammad Sharif, Hajra Arshad Mallick, Muhammad Zahoor, Fareeha Abdulmalik, Attiya Baig, Warda Shujaat, Nodia Gul, Sundas Bibi, Gulfam Ramzan, Rahdia Murtaza, Ghulam |
| description | Capsicum annuum L. is a rich source of capsaicin, an alkaloid, which is a very pungent compound. Due to ever growing need of capsaicin, an extensive research on its efficient cultivation as well as chemical synthesis is underway. Owing to the pungent nature of capsaicin, its analogous molecules without pungent effect are being explored. The objective of this descriptive review is to comprehensively present the updates on the bioactivities of capsaicin. Additionally, the in silico target fishing approach has been used to identify the possible protein targets of capsaicin. This article will definitely provide future perspectives of research on capsaicin. |
| format | Article |
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Due to ever growing need of capsaicin, an extensive research on its efficient cultivation as well as chemical synthesis is underway. Owing to the pungent nature of capsaicin, its analogous molecules without pungent effect are being explored. The objective of this descriptive review is to comprehensively present the updates on the bioactivities of capsaicin. Additionally, the in silico target fishing approach has been used to identify the possible protein targets of capsaicin. 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Due to ever growing need of capsaicin, an extensive research on its efficient cultivation as well as chemical synthesis is underway. Owing to the pungent nature of capsaicin, its analogous molecules without pungent effect are being explored. The objective of this descriptive review is to comprehensively present the updates on the bioactivities of capsaicin. Additionally, the in silico target fishing approach has been used to identify the possible protein targets of capsaicin. This article will definitely provide future perspectives of research on capsaicin.</description><subject>Animals</subject><subject>Capsaicin - adverse effects</subject><subject>Capsaicin - chemistry</subject><subject>Capsaicin - pharmacokinetics</subject><subject>Capsaicin - therapeutic use</subject><subject>Computational Biology - methods</subject><subject>Computer Simulation</subject><subject>Humans</subject><subject>Molecular Structure</subject><subject>Molecular Targeted Therapy - adverse effects</subject><subject>Molecular Targeted Therapy - methods</subject><subject>Protein Interaction Maps</subject><subject>Signal Transduction - drug effects</subject><subject>Structure-Activity Relationship</subject><issn>0001-6837</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2017</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNo1j0FrgzAYhnPYWEvXvzBy3EVIPhNjdsucbT8QHdPtKhoz6NDVmXrYv1-h7vTywMMD7w1ZM8Z4EMWhWpGt918XZFIozfkdWYGOQECo1sQk5rU0mGD-RLEq6TMWWbHHxGTUJBV-YIVpSU3-QjGnJWaYFLQyb_u0ojssD5jv78ntZ9N7t112Q953aZUcgqUTjMD5OWhY5GzHXSOlbri0CoCFTllrBUQubpXkLOoUKCEjobUGC61snRVOxq1TXbghj9fuOJ1-ZufP9XD01vV98-1Os6-BAWilhWAX9WFR53ZwXT1Ox6GZfuv_2-EfcQ1L8w</recordid><startdate>20170301</startdate><enddate>20170301</enddate><creator>Akhtar, Fahad</creator><creator>Muhammad Sharif, Hajra</creator><creator>Arshad Mallick, Muhammad</creator><creator>Zahoor, Fareeha</creator><creator>Abdulmalik, Attiya</creator><creator>Baig, Warda</creator><creator>Shujaat, Nodia</creator><creator>Gul, Sundas</creator><creator>Bibi, Gulfam</creator><creator>Ramzan, Rahdia</creator><creator>Murtaza, Ghulam</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope></search><sort><creationdate>20170301</creationdate><title>CAPSAICIN: ITS BIOLOGICAL ACTIVITIES AND IN SILICO TARGET FISHING</title><author>Akhtar, Fahad ; Muhammad Sharif, Hajra ; Arshad Mallick, Muhammad ; Zahoor, Fareeha ; Abdulmalik, Attiya ; Baig, Warda ; Shujaat, Nodia ; Gul, Sundas ; Bibi, Gulfam ; Ramzan, Rahdia ; Murtaza, Ghulam</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-p211t-a06ecd1ea559a15c72203e7ccc426e8b75106d72745649992c2b5bec4e58be7d3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2017</creationdate><topic>Animals</topic><topic>Capsaicin - adverse effects</topic><topic>Capsaicin - chemistry</topic><topic>Capsaicin - pharmacokinetics</topic><topic>Capsaicin - therapeutic use</topic><topic>Computational Biology - methods</topic><topic>Computer Simulation</topic><topic>Humans</topic><topic>Molecular Structure</topic><topic>Molecular Targeted Therapy - adverse effects</topic><topic>Molecular Targeted Therapy - methods</topic><topic>Protein Interaction Maps</topic><topic>Signal Transduction - drug effects</topic><topic>Structure-Activity Relationship</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Akhtar, Fahad</creatorcontrib><creatorcontrib>Muhammad Sharif, Hajra</creatorcontrib><creatorcontrib>Arshad Mallick, Muhammad</creatorcontrib><creatorcontrib>Zahoor, Fareeha</creatorcontrib><creatorcontrib>Abdulmalik, Attiya</creatorcontrib><creatorcontrib>Baig, Warda</creatorcontrib><creatorcontrib>Shujaat, Nodia</creatorcontrib><creatorcontrib>Gul, Sundas</creatorcontrib><creatorcontrib>Bibi, Gulfam</creatorcontrib><creatorcontrib>Ramzan, Rahdia</creatorcontrib><creatorcontrib>Murtaza, Ghulam</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><jtitle>Acta Poloniae pharmaceutica</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Akhtar, Fahad</au><au>Muhammad Sharif, Hajra</au><au>Arshad Mallick, Muhammad</au><au>Zahoor, Fareeha</au><au>Abdulmalik, Attiya</au><au>Baig, Warda</au><au>Shujaat, Nodia</au><au>Gul, Sundas</au><au>Bibi, Gulfam</au><au>Ramzan, Rahdia</au><au>Murtaza, Ghulam</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>CAPSAICIN: ITS BIOLOGICAL ACTIVITIES AND IN SILICO TARGET FISHING</atitle><jtitle>Acta Poloniae pharmaceutica</jtitle><addtitle>Acta Pol Pharm</addtitle><date>2017-03-01</date><risdate>2017</risdate><volume>74</volume><issue>2</issue><spage>321</spage><epage>329</epage><pages>321-329</pages><issn>0001-6837</issn><abstract>Capsicum annuum L. is a rich source of capsaicin, an alkaloid, which is a very pungent compound. 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| source | MEDLINE; DOAJ Directory of Open Access Journals; EZB-FREE-00999 freely available EZB journals |
| subjects | Animals Capsaicin - adverse effects Capsaicin - chemistry Capsaicin - pharmacokinetics Capsaicin - therapeutic use Computational Biology - methods Computer Simulation Humans Molecular Structure Molecular Targeted Therapy - adverse effects Molecular Targeted Therapy - methods Protein Interaction Maps Signal Transduction - drug effects Structure-Activity Relationship |
| title | CAPSAICIN: ITS BIOLOGICAL ACTIVITIES AND IN SILICO TARGET FISHING |
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