Dampening of IL-2 Function in Infants With Severe Respiratory Syncytial Virus Disease

FOXP3+ regulatory T cells (Tregs) restrain the destructive potential of the immune system. We have previously reported a pronounced reduction in circulating Tregs in infants with severe respiratory syncytial virus (RSV) disease. Because interleukin-2 (IL-2) is critical for Treg growth, survival, and...

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Veröffentlicht in:	The Journal of infectious diseases 2018-06, Vol.218 (1), p.75-83
Hauptverfasser:	Sananez, Inés, Raiden, Silvina, Erra-Díaz, Fernando, De Lillo, Leonardo, Holgado, María Pía, Geffner, Jorge, Arruvito, Lourdes
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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