Role of altered immune cells in liver diseases: a review
Abstract Immune cells play an important role in controlling liver tumorigenesis, viral hepatitis, liver fibrosis and contribute to pathogenesis of liver inflammation and injury. Accumulating evidence suggests the effectiveness of natural killer (NK) cells and Kupffer cells (KCs) against viral hepati...
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| Veröffentlicht in: | Gastroenterología y hepatología 2018-06, Vol.41 (6), p.377-388 |
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| container_end_page | 388 |
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| container_issue | 6 |
| container_start_page | 377 |
| container_title | Gastroenterología y hepatología |
| container_volume | 41 |
| creator | Wahid, Braira Ali, Amjad Rafique, Shazia Saleem, Komal Waqar, Muhammad Wasim, Muhammad Idrees, Muhammad |
| description | Abstract Immune cells play an important role in controlling liver tumorigenesis, viral hepatitis, liver fibrosis and contribute to pathogenesis of liver inflammation and injury. Accumulating evidence suggests the effectiveness of natural killer (NK) cells and Kupffer cells (KCs) against viral hepatitis, hepatocellular damage, liver fibrosis, and carcinogenesis. Activation of natural killer cells provides a novel therapeutic strategy to cure liver related diseases. This review discusses the emerging roles of immune cells in liver disorders and it will provide baseline data to scientists to design better therapies for treatment. |
| doi_str_mv | 10.1016/j.gastrohep.2018.01.014 |
| format | Article |
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Accumulating evidence suggests the effectiveness of natural killer (NK) cells and Kupffer cells (KCs) against viral hepatitis, hepatocellular damage, liver fibrosis, and carcinogenesis. Activation of natural killer cells provides a novel therapeutic strategy to cure liver related diseases. This review discusses the emerging roles of immune cells in liver disorders and it will provide baseline data to scientists to design better therapies for treatment.</description><identifier>ISSN: 0210-5705</identifier><identifier>DOI: 10.1016/j.gastrohep.2018.01.014</identifier><identifier>PMID: 29605453</identifier><language>eng</language><publisher>Spain: Elsevier España, S.L.U</publisher><subject>Animals ; Cirrhosis ; Cirrosis ; Células de Kupffer ; Células dendríticas ; Células NK ; Dendritic cells ; Disease Models, Animal ; Gastroenterology and Hepatology ; Hepatic stellate cells ; Humans ; Hígado ; Immune System - cytology ; Immune System - immunology ; Liver ; Liver Diseases - immunology ; NK Cells</subject><ispartof>Gastroenterología y hepatología, 2018-06, Vol.41 (6), p.377-388</ispartof><rights>Elsevier España, S.L.U.</rights><rights>2018 Elsevier España, S.L.U.</rights><rights>Copyright © 2018 Elsevier España, S.L.U. 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| fulltext | fulltext |
| identifier | ISSN: 0210-5705 |
| ispartof | Gastroenterología y hepatología, 2018-06, Vol.41 (6), p.377-388 |
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| language | eng |
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| source | MEDLINE; Elsevier ScienceDirect Journals Complete; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals |
| subjects | Animals Cirrhosis Cirrosis Células de Kupffer Células dendríticas Células NK Dendritic cells Disease Models, Animal Gastroenterology and Hepatology Hepatic stellate cells Humans Hígado Immune System - cytology Immune System - immunology Liver Liver Diseases - immunology NK Cells |
| title | Role of altered immune cells in liver diseases: a review |
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