Inhibitory Effect of (−)-Epigallocatechin-3-O-gallate on Octanoylated Ghrelin Levels in Vitro and in Vivo

Ghrelin is an orexigenic peptide hormone produced in the stomach. The major active form is octanoylated ghrelin, which is modified with an n-octanoic acid at the serine-3 residue. Inhibition of octanoylated ghrelin production is useful for the prevention and improvement of obesity. We previously dev...

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Veröffentlicht in:	Biological & pharmaceutical bulletin 2018/04/01, Vol.41(4), pp.524-529
Hauptverfasser:	Nakajima, Kensuke, Oiso, Shigeru, Kariyazono, Hiroko
Format:	Artikel
Sprache:	eng
Schlagworte:	(−)-epigallocatechin-3-O-gallate (EGCG) AGS-GHRL8 cell Catechin Epigallocatechin gallate Gene expression Ghrelin Green tea Inhibition Mice Obesity Octanoic acid octanoylated ghrelin Proprotein convertases Rodents Serine Stomach Tea
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