Preclinical Studies of Stem Cell Therapy for Heart Disease
As part of the TACTICS (Transnational Alliance for Regenerative Therapies in Cardiovascular Syndromes) series to enhance regenerative medicine, here, we discuss the role of preclinical studies designed to advance stem cell therapies for cardiovascular disease. The quality of this research has improv...
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| Veröffentlicht in: | Circulation research 2018-03, Vol.122 (7), p.1006-1020 |
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| container_end_page | 1020 |
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| container_issue | 7 |
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| container_title | Circulation research |
| container_volume | 122 |
| creator | Tompkins, Bryon A Balkan, Wayne Winkler, Johannes Gyöngyösi, Mariann Goliasch, Georg Fernández-Avilés, Francisco Hare, Joshua M |
| description | As part of the TACTICS (Transnational Alliance for Regenerative Therapies in Cardiovascular Syndromes) series to enhance regenerative medicine, here, we discuss the role of preclinical studies designed to advance stem cell therapies for cardiovascular disease. The quality of this research has improved over the past 10 to 15 years and overall indicates that cell therapy promotes cardiac repair. However, many issues remain, including inability to provide complete cardiac recovery. Recent studies question the need for intact cells suggesting that harnessing what the cells release is the solution. Our contribution describes important breakthroughs and current directions in a cell-based approach to alleviating cardiovascular disease. |
| doi_str_mv | 10.1161/CIRCRESAHA.117.312486 |
| format | Article |
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| fulltext | fulltext |
| identifier | ISSN: 0009-7330 |
| ispartof | Circulation research, 2018-03, Vol.122 (7), p.1006-1020 |
| issn | 0009-7330 1524-4571 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_2020492972 |
| source | Journals@Ovid Ovid Autoload; American Heart Association Journals; EZB-FREE-00999 freely available EZB journals |
| subjects | Cardiovascular disease Coronary artery disease Heart diseases Regenerative medicine Stem cells Tissue engineering |
| title | Preclinical Studies of Stem Cell Therapy for Heart Disease |
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