Postconditioning effects of argon or xenon on early graft function in a porcine model of kidney autotransplantation

Background Ischaemia–reperfusion injury is inevitable during renal transplantation and can lead to delayed graft function and primary non‐function. Preconditioning, reconditioning and postconditioning with argon and xenon protects against renal ischaemia–reperfusion injury in rodent models. The hypo...

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Veröffentlicht in:	British journal of surgery 2018-07, Vol.105 (8), p.1051-1060
Hauptverfasser:	De Deken, J., Rex, S., Lerut, E., Martinet, W., Monbaliu, D., Pirenne, J., Jochmans, I.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animal research Animals Apoptosis - drug effects Argon - pharmacology Autophagy Biomarkers - metabolism Female Graft Survival - drug effects Histology Hypotheses Ischemic Postconditioning - adverse effects Ischemic Postconditioning - methods Kidney - physiopathology Kidney - surgery Kidney Function Tests - methods Kidney Transplantation - adverse effects Kidney Transplantation - methods Kruskal-Wallis test Models, Animal Real-Time Polymerase Chain Reaction Reperfusion Injury - prevention & control Rodents Survival Rate Swine Transplantation, Autologous - adverse effects Transplantation, Autologous - methods Urine Xenon - pharmacology
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