Ultracompact high-resolution photoacoustic microscopy
Optical resolution photoacoustic microscopy (ORPAM), benefiting from rich optical contrast, scalable acoustic resolution, and deep penetration depth, is of great importance for the fields of biology and medicine. However, limited by the size and performance of reported optical/acoustic scanners, exi...
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| Veröffentlicht in: | Optics letters 2018-04, Vol.43 (7), p.1615-1618 |
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| container_title | Optics letters |
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| creator | Chen, Qian Guo, Heng Jin, Tian Qi, Weizhi Xie, Huikai Xi, Lei |
| description | Optical resolution photoacoustic microscopy (ORPAM), benefiting from rich optical contrast, scalable acoustic resolution, and deep penetration depth, is of great importance for the fields of biology and medicine. However, limited by the size and performance of reported optical/acoustic scanners, existing portable/handheld ORPAMs are bulky and heavy, and suffer from low imaging quality/speed. Here, we present an ultracompact ORPAM probe, which is miniature and light, and has high imaging quality. The probe only weighs 20 grams and has an outer size of 22 mm×30 mm×13 mm, a high lateral resolution of 3.8 μm, and an effective imaging domain of 2 mm×2 mm. To show its advantages over existing ORPAMs, we apply this probe to image vasculatures of internal organs in a rat abdominal cavity and inspect the entire human oral cavity. |
| doi_str_mv | 10.1364/OL.43.001615 |
| format | Article |
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However, limited by the size and performance of reported optical/acoustic scanners, existing portable/handheld ORPAMs are bulky and heavy, and suffer from low imaging quality/speed. Here, we present an ultracompact ORPAM probe, which is miniature and light, and has high imaging quality. The probe only weighs 20 grams and has an outer size of 22 mm×30 mm×13 mm, a high lateral resolution of 3.8 μm, and an effective imaging domain of 2 mm×2 mm. 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| fulltext | fulltext |
| identifier | ISSN: 0146-9592 |
| ispartof | Optics letters, 2018-04, Vol.43 (7), p.1615-1618 |
| issn | 0146-9592 1539-4794 |
| language | eng |
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| source | Optica Publishing Group Journals |
| subjects | Acoustic microscopy Imaging Microscopy Optical scanners Organs Penetration depth Photoacoustic microscopy |
| title | Ultracompact high-resolution photoacoustic microscopy |
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