Amniotic membrane extract differentially regulates human peripheral blood T cell subsets, monocyte subpopulations and myeloid dendritic cells

The discovery of the immunoregulatory potential of human amniotic membrane (hAM) propelled several studies focusing on its application for the treatment of immunological disorders. However, there is little information regarding the effects of hAM on distinct activation and differentiation stages of...

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Veröffentlicht in:	Cell and tissue research 2018-08, Vol.373 (2), p.459-476
Hauptverfasser:	Laranjeira, Paula, Duque, Marta, Vojtek, Martin, Inácio, Maria J., Silva, Isabel, Mamede, Ana C., Laranjo, Mafalda, Pedreiro, Susana, Carvalho, Maria J., Moura, Paulo, Abrantes, Ana M., Maia, Cláudio J., Domingues, Pedro, Domingues, Rosário, Martinho, António, Botelho, Maria F., Trindade, Hélder, Paiva, Artur
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Amnion - metabolism Amniotic membrane Biomedical and Life Sciences Biomedicine CD4 antigen CD8 antigen Cell Proliferation - drug effects Cytokines Dendritic cells Dendritic Cells - cytology Dendritic Cells - drug effects Extracellular matrix Female Foxp3 protein Gene expression Granzyme B Human Genetics Humans Immunoregulation Inflammation Interferon Interferon-gamma - metabolism Interleukin 10 Interleukin 17 Interleukin 6 Interleukin 9 Interleukin-17 - metabolism Interleukin-2 - metabolism Interleukin-9 - metabolism Leukocytes (mononuclear) Lymphocyte Count Lymphocytes Lymphocytes T Male Middle Aged Mitogens - pharmacology Molecular Medicine Monocytes Monocytes - cytology Monocytes - drug effects Myeloid Cells - cytology Myeloid Cells - drug effects Perforin Peripheral blood mononuclear cells Proteomics Regular Article RNA, Messenger - genetics RNA, Messenger - metabolism T cells T-Lymphocyte Subsets - cytology T-Lymphocyte Subsets - drug effects Transcription, Genetic - drug effects Tumor Necrosis Factor-alpha - metabolism Tumor necrosis factor-TNF Tumor necrosis factor-α Young Adult γ-Interferon
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