In Situ Inner Lumen Attachment of Heparin to Poly(ether sulfone) Hollow Fiber Membranes Used for Microdialysis Sampling

An in situ chemical surface modification method to attach heparin to the inner lumen of a single hollow fiber poly(ether sulfone) (PES) membrane incorporated into a commercial microdialysis sampling device is described. The immobilization process uses gentle, room-temperature conditions with the en...

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Veröffentlicht in:	Analytical chemistry (Washington) 2018-04, Vol.90 (8), p.4955-4960
Hauptverfasser:	Phillips, Sarah J, Stenken, Julie A
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Anticoagulants Chemistry Chemokine CXCL1 - isolation & purification Cytokines Dextrans Fibroblast Growth Factor 1 - isolation & purification Fluorescein Functional groups Growth factors Heparin - chemistry Hollow fiber membranes Laccase Laccase - metabolism Lysozyme Membranes Membranes, Artificial Mice Microdialysis - methods Muramidase - isolation & purification Organic chemistry Parabens - chemistry Parabens - metabolism Photoelectron Spectroscopy Polymers Polymers - chemistry Rats Sampling Spectrum analysis Sulfones - chemistry Surface Properties
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