Effects of Stigmasterol and β‑Sitosterol on Nonalcoholic Fatty Liver Disease in a Mouse Model: A Lipidomic Analysis

To study the effects of stigmasterol and β-sitosterol on high-fat Western diet (HFWD)-induced nonalcoholic fatty liver disease (NAFLD), lipidomic analyses were conducted in liver samples collected after 33 weeks of the treatment. Principal component analysis showed these phytosterols were effective...

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Veröffentlicht in:	Journal of agricultural and food chemistry 2018-04, Vol.66 (13), p.3417-3425
Hauptverfasser:	Feng, Simin, Gan, Ling, Yang, Chung S, Liu, Anna B, Lu, Wenyun, Shao, Ping, Dai, Zhuqing, Sun, Peilong, Luo, Zisheng
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cholesterol - metabolism Diet, High-Fat - adverse effects Disease Models, Animal Humans Lipid Metabolism - drug effects Liver - drug effects Liver - metabolism Male Mice Mice, Inbred C57BL Non-alcoholic Fatty Liver Disease - drug therapy Non-alcoholic Fatty Liver Disease - metabolism Sitosterols - administration & dosage Stigmasterol - administration & dosage Triglycerides - metabolism
Online-Zugang:	Volltext
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