Magnolia officinalis (Hou Po) bark extract stimulates the Nrf2-pathway in hepatocytes and protects against oxidative stress

The highly aromatic bark of Magnolia officinalis Rehder and EH Wilson, (magnolia bark) has been widely used in traditional Chinese medicine where it is known as Hou Po. Historically the bark of the tree has been used for treating variety of disorders the most common use of magnolia bark in tradition...

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Veröffentlicht in:	Journal of ethnopharmacology 2016-12, Vol.193 (NA), p.657-662
Hauptverfasser:	Rajgopal, Arun, Missler, Stephen R, Scholten, Jeffery D
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antioxidant response elements (AREs) Antioxidant Response Elements - genetics Cell Survival - drug effects Gene Expression - drug effects Genes, Reporter Hep G2 Cells Hepatocytes - drug effects Hepatocytes - immunology Hepatocytes - metabolism Humans Luciferases - genetics Magnolia (Magnolia officinalis) bark extract Magnolia - chemistry Mice NF-E2-Related Factor 2 - genetics Nuclear factor E2-related factor 2 (Nrf2) Oxidative stress Oxidative Stress - drug effects Oxidative Stress - genetics Phytochemicals Plant Bark - chemistry Quinone reductase Transfection
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