Sustained Response Following Discontinuation of Methotrexate in Patients With Rheumatoid Arthritis Treated With Subcutaneous Tocilizumab: Results From a Randomized, Controlled Trial

To evaluate whether tocilizumab (TCZ) monotherapy is noninferior to treatment with TCZ plus methotrexate (MTX) for maintaining clinical responses in patients with rheumatoid arthritis (RA) in whom low disease activity is achieved with TCZ plus MTX. Patients with RA who experienced an inadequate resp...

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Veröffentlicht in:	Arthritis & rheumatology (Hoboken, N.J.) N.J.), 2018-08, Vol.70 (8), p.1200-1208
Hauptverfasser:	Kremer, Joel M, Rigby, William, Singer, Nora G, Birchwood, Christine, Gill, Darcy, Reiss, William, Pei, Jinglan, Michalska, Margaret
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Antibodies, Monoclonal, Humanized - administration & dosage Antirheumatic Agents - administration & dosage Arthritis, Rheumatoid - drug therapy Arthritis, Rheumatoid - pathology Disease Progression Double-Blind Method Drug Therapy, Combination Female Humans Male Methotrexate - administration & dosage Middle Aged Time Factors Treatment Outcome Withholding Treatment
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