Humoral immunity 10 years after booster immunization with an adolescent and adult formulation combined tetanus, diphtheria, and 5-component acellular pertussis vaccine in the USA

Humoral immunity 10 years after booster immunization with an adolescent and adult formulation combined tetanus, diphtheria, and 5-component acellular pertussis vaccine in the USA

•Tdap and Td provide long-lasting protective responses against diphtheria and tetanus.•PT antibodies returned to pre-vaccination levels by 5 years post-vaccination.•Adolescents and adults had similar profiles for persistence of pertussis antibodies. In a prospective, randomized pivotal phase III cli...

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Bibliographische Detailangaben
Veröffentlicht in:Vaccine 2018-04, Vol.36 (17), p.2282-2287
Hauptverfasser: Pool, Vitali, Tomovici, Antigona, Johnson, David R., Greenberg, David P., Decker, Michael D.
Format: Artikel
Sprache:eng
Schlagworte:
Adolescents
Adults
Age
Aluminum
Antibodies
Antibody persistence
Bleeding
Combined vaccines
Data collection
Diphtheria
FDA approval
Humoral immunity
Hypothesis testing
Immune response
Immunity
Immunization
Immunogenicity
Immunoglobulins
Immunology
Laboratories
Pertussis
Population
Serology
Teenagers
Tetanus
Vaccination
Vaccines
Whooping cough
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