Novel angiogenesis therapeutics by redox injectable hydrogel - Regulation of local nitric oxide generation for effective cardiovascular therapy

Nitric oxide (NO) possesses various functions in cardiovascular diseases; however, due to an extremely short half-life and low bioavailability, its therapeutic application is limited. In inflamed tissues, overproduced reactive oxygen species (ROS) rapidly react with the endogenous NO, reducing its b...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Biomaterials 2018-06, Vol.167, p.143-152
Hauptverfasser:	Vong, Long Binh, Bui, Thang Quoc, Tomita, Tsutomu, Sakamoto, Hiroaki, Hiramatsu, Yuji, Nagasaki, Yukio
Format:	Artikel
Sprache:	eng
Schlagworte:	Angiogenesis Inducing Agents - administration & dosage Angiogenesis Inducing Agents - therapeutic use Animals Delayed-Action Preparations - chemistry Hydrogels - chemistry Injections Male Mice Mice, Inbred ICR Myocardial infarction Myocardial Infarction - drug therapy Myocardial Infarction - metabolism Myocardial Infarction - pathology Nitric Oxide - metabolism Nitric oxide delivery Nitric Oxide Donors - administration & dosage Nitric Oxide Donors - therapeutic use Oxidation-Reduction Polyion complex micelle RAW 264.7 Cells Reactive oxygen species Reactive Oxygen Species - metabolism Redox injectable hydrogel
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!