Curative Criteria After Endoscopic Resection for Superficial Esophageal Squamous Cell Carcinomas
Background According to the Japanese Esophageal Society (JES) guidelines, risk factors for lymph node (LN) metastasis in the muscularis mucosa (MM)/submucosa to a depth of up to 200 μm (SM1) in cases of esophageal squamous cell carcinomas (ESCCs) include the presence of lymphatic invasion (ly), veno...
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| Veröffentlicht in: | Digestive diseases and sciences 2018-06, Vol.63 (6), p.1605-1612 |
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| creator | Mizumoto, T. Hiyama, T. Oka, S. Yorita, N. Kuroki, K. Kurihara, M. Yoshifuku, Y. Sanomura, Y. Urabe, Y. Murakami, Y. Arihiro, K. Tanaka, S. Chayama, K. |
| description | Background
According to the Japanese Esophageal Society (JES) guidelines, risk factors for lymph node (LN) metastasis in the muscularis mucosa (MM)/submucosa to a depth of up to 200 μm (SM1) in cases of esophageal squamous cell carcinomas (ESCCs) include the presence of lymphatic invasion (ly), venous invasion (v), infiltration pattern (INF)c, and SM1. The long-term prognoses of these patients are unclear, and there are very few reports on the validation of the curative criteria for MM/SM1 ESCCs.
Aims
To examine the long-term prognoses of these patients and the risk factors for LN metastasis of MM/SM1 ESCCs after endoscopic resection (ER).
Methods
This study included patients with MM/SM1 ESCCs who underwent ER at Hiroshima University Hospital from December 1990 to November 2016. We evaluated the clinicopathological characteristics of 98 patients and overall survival, disease-specific survival, recurrence-free survival, and recurrence rates in the e-curative and non-e-curative groups.
Results
The mean observation period was 75 months. There was no significant difference in disease-specific survival rate between the e-curative and non-e-curative groups (100 vs. 98%). There was no significant difference in disease-specific survival rates between the groups (100 vs. 98%). In contrast, the LN recurrence-free survival rate in patients with INFa, ly(−), and v(−) was significantly higher than that in patients with INFb/c, ly(+), or v(+) (100 and 87%,
P
|
| doi_str_mv | 10.1007/s10620-018-5029-0 |
| format | Article |
| fullrecord | <record><control><sourceid>gale_proqu</sourceid><recordid>TN_cdi_proquest_miscellaneous_2017055089</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><galeid>A712938080</galeid><sourcerecordid>A712938080</sourcerecordid><originalsourceid>FETCH-LOGICAL-c632t-3d3a8c6009e8696a5e045422a360589d31bc4522ee663a27dcd378c8e85edde3</originalsourceid><addsrcrecordid>eNp1kU9rFTEUxYMo9ln9AG4k4KabaW-Slz-zfAyvKhSEtvuYZu48U2Ym02Sm4Lc3w6sWRcniXpLfOZxwCHnP4JwB6IvMQHGogJlKAq8reEE2TGpRcanMS7IBpsrOmDohb3K-B4BaM_WanPBaqq3SsCHfmiW5OTwibVKYMQVHd12ZdD-2Mfs4BU-vMaOfQxxpFxO9WSZMXfDB9XSf4_TdHbCsNw-LG-KSaYN9TxuXfBjj4PJb8qpzfcZ3T_OU3F7ub5vP1dXXT1-a3VXlleBzJVrhjFclIRpVKycRtnLLuRMKpKlbwe78VnKOqJRwXLe-Fdp4g0Zi26I4JWdH2ynFhwXzbIeQfYniRiypLAemQUowdUE__oXexyWNJdxKKaYlCPNMHVyPNoxdnJPzq6ndacZrYcBAoc7_QZXT4hB8HLEL5f4PATsKfIo5J-zslMLg0g_LwK6l2mOptpRq11LtqvnwFHi5G7D9rfjVYgH4EcjlaTxgev7R_11_AihXqiI</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2016175038</pqid></control><display><type>article</type><title>Curative Criteria After Endoscopic Resection for Superficial Esophageal Squamous Cell Carcinomas</title><source>MEDLINE</source><source>Springer Nature - Complete Springer Journals</source><creator>Mizumoto, T. ; Hiyama, T. ; Oka, S. ; Yorita, N. ; Kuroki, K. ; Kurihara, M. ; Yoshifuku, Y. ; Sanomura, Y. ; Urabe, Y. ; Murakami, Y. ; Arihiro, K. ; Tanaka, S. ; Chayama, K.</creator><creatorcontrib>Mizumoto, T. ; Hiyama, T. ; Oka, S. ; Yorita, N. ; Kuroki, K. ; Kurihara, M. ; Yoshifuku, Y. ; Sanomura, Y. ; Urabe, Y. ; Murakami, Y. ; Arihiro, K. ; Tanaka, S. ; Chayama, K.</creatorcontrib><description>Background
According to the Japanese Esophageal Society (JES) guidelines, risk factors for lymph node (LN) metastasis in the muscularis mucosa (MM)/submucosa to a depth of up to 200 μm (SM1) in cases of esophageal squamous cell carcinomas (ESCCs) include the presence of lymphatic invasion (ly), venous invasion (v), infiltration pattern (INF)c, and SM1. The long-term prognoses of these patients are unclear, and there are very few reports on the validation of the curative criteria for MM/SM1 ESCCs.
Aims
To examine the long-term prognoses of these patients and the risk factors for LN metastasis of MM/SM1 ESCCs after endoscopic resection (ER).
Methods
This study included patients with MM/SM1 ESCCs who underwent ER at Hiroshima University Hospital from December 1990 to November 2016. We evaluated the clinicopathological characteristics of 98 patients and overall survival, disease-specific survival, recurrence-free survival, and recurrence rates in the e-curative and non-e-curative groups.
Results
The mean observation period was 75 months. There was no significant difference in disease-specific survival rate between the e-curative and non-e-curative groups (100 vs. 98%). There was no significant difference in disease-specific survival rates between the groups (100 vs. 98%). In contrast, the LN recurrence-free survival rate in patients with INFa, ly(−), and v(−) was significantly higher than that in patients with INFb/c, ly(+), or v(+) (100 and 87%,
P
< 0.05).
Conclusion
Contrary to the JES guidelines, our findings suggest that new criteria (MM/SM1, INFa, negative vertical margin (VM0), ly[-], and v[-]) may be associated with curative ER without additional treatment.</description><identifier>ISSN: 0163-2116</identifier><identifier>EISSN: 1573-2568</identifier><identifier>DOI: 10.1007/s10620-018-5029-0</identifier><identifier>PMID: 29564670</identifier><language>eng</language><publisher>New York: Springer US</publisher><subject>Aged ; Biochemistry ; Carcinoma, Squamous Cell - mortality ; Carcinoma, Squamous Cell - secondary ; Carcinoma, Squamous Cell - surgery ; Disease Progression ; Disease-Free Survival ; Endoscopy ; Esophageal cancer ; Esophageal Neoplasms - mortality ; Esophageal Neoplasms - pathology ; Esophageal Neoplasms - surgery ; Esophageal Squamous Cell Carcinoma ; Esophagectomy - adverse effects ; Esophagectomy - methods ; Esophagectomy - mortality ; Esophagoscopy - adverse effects ; Esophagoscopy - mortality ; Esophagus ; Female ; Gastroenterology ; Hepatology ; Hospitals, University ; Humans ; Japan ; Kaplan-Meier Estimate ; Lymphatic Metastasis ; Male ; Medical prognosis ; Medical research ; Medicine ; Medicine & Public Health ; Medicine, Experimental ; Metastasis ; Middle Aged ; Neoplasm Invasiveness ; Neoplasm Recurrence, Local ; Oncology ; Original Article ; Prognosis ; Retrospective Studies ; Risk Factors ; Squamous cell carcinoma ; Surgery ; Time Factors ; Transplant Surgery ; Treatment Outcome</subject><ispartof>Digestive diseases and sciences, 2018-06, Vol.63 (6), p.1605-1612</ispartof><rights>Springer Science+Business Media, LLC, part of Springer Nature 2018</rights><rights>COPYRIGHT 2018 Springer</rights><rights>Digestive Diseases and Sciences is a copyright of Springer, (2018). All Rights Reserved.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c632t-3d3a8c6009e8696a5e045422a360589d31bc4522ee663a27dcd378c8e85edde3</citedby><cites>FETCH-LOGICAL-c632t-3d3a8c6009e8696a5e045422a360589d31bc4522ee663a27dcd378c8e85edde3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s10620-018-5029-0$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s10620-018-5029-0$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,780,784,27915,27916,41479,42548,51310</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/29564670$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Mizumoto, T.</creatorcontrib><creatorcontrib>Hiyama, T.</creatorcontrib><creatorcontrib>Oka, S.</creatorcontrib><creatorcontrib>Yorita, N.</creatorcontrib><creatorcontrib>Kuroki, K.</creatorcontrib><creatorcontrib>Kurihara, M.</creatorcontrib><creatorcontrib>Yoshifuku, Y.</creatorcontrib><creatorcontrib>Sanomura, Y.</creatorcontrib><creatorcontrib>Urabe, Y.</creatorcontrib><creatorcontrib>Murakami, Y.</creatorcontrib><creatorcontrib>Arihiro, K.</creatorcontrib><creatorcontrib>Tanaka, S.</creatorcontrib><creatorcontrib>Chayama, K.</creatorcontrib><title>Curative Criteria After Endoscopic Resection for Superficial Esophageal Squamous Cell Carcinomas</title><title>Digestive diseases and sciences</title><addtitle>Dig Dis Sci</addtitle><addtitle>Dig Dis Sci</addtitle><description>Background
According to the Japanese Esophageal Society (JES) guidelines, risk factors for lymph node (LN) metastasis in the muscularis mucosa (MM)/submucosa to a depth of up to 200 μm (SM1) in cases of esophageal squamous cell carcinomas (ESCCs) include the presence of lymphatic invasion (ly), venous invasion (v), infiltration pattern (INF)c, and SM1. The long-term prognoses of these patients are unclear, and there are very few reports on the validation of the curative criteria for MM/SM1 ESCCs.
Aims
To examine the long-term prognoses of these patients and the risk factors for LN metastasis of MM/SM1 ESCCs after endoscopic resection (ER).
Methods
This study included patients with MM/SM1 ESCCs who underwent ER at Hiroshima University Hospital from December 1990 to November 2016. We evaluated the clinicopathological characteristics of 98 patients and overall survival, disease-specific survival, recurrence-free survival, and recurrence rates in the e-curative and non-e-curative groups.
Results
The mean observation period was 75 months. There was no significant difference in disease-specific survival rate between the e-curative and non-e-curative groups (100 vs. 98%). There was no significant difference in disease-specific survival rates between the groups (100 vs. 98%). In contrast, the LN recurrence-free survival rate in patients with INFa, ly(−), and v(−) was significantly higher than that in patients with INFb/c, ly(+), or v(+) (100 and 87%,
P
< 0.05).
Conclusion
Contrary to the JES guidelines, our findings suggest that new criteria (MM/SM1, INFa, negative vertical margin (VM0), ly[-], and v[-]) may be associated with curative ER without additional treatment.</description><subject>Aged</subject><subject>Biochemistry</subject><subject>Carcinoma, Squamous Cell - mortality</subject><subject>Carcinoma, Squamous Cell - secondary</subject><subject>Carcinoma, Squamous Cell - surgery</subject><subject>Disease Progression</subject><subject>Disease-Free Survival</subject><subject>Endoscopy</subject><subject>Esophageal cancer</subject><subject>Esophageal Neoplasms - mortality</subject><subject>Esophageal Neoplasms - pathology</subject><subject>Esophageal Neoplasms - surgery</subject><subject>Esophageal Squamous Cell Carcinoma</subject><subject>Esophagectomy - adverse effects</subject><subject>Esophagectomy - methods</subject><subject>Esophagectomy - mortality</subject><subject>Esophagoscopy - adverse effects</subject><subject>Esophagoscopy - mortality</subject><subject>Esophagus</subject><subject>Female</subject><subject>Gastroenterology</subject><subject>Hepatology</subject><subject>Hospitals, University</subject><subject>Humans</subject><subject>Japan</subject><subject>Kaplan-Meier Estimate</subject><subject>Lymphatic Metastasis</subject><subject>Male</subject><subject>Medical prognosis</subject><subject>Medical research</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Medicine, Experimental</subject><subject>Metastasis</subject><subject>Middle Aged</subject><subject>Neoplasm Invasiveness</subject><subject>Neoplasm Recurrence, Local</subject><subject>Oncology</subject><subject>Original Article</subject><subject>Prognosis</subject><subject>Retrospective Studies</subject><subject>Risk Factors</subject><subject>Squamous cell carcinoma</subject><subject>Surgery</subject><subject>Time Factors</subject><subject>Transplant Surgery</subject><subject>Treatment Outcome</subject><issn>0163-2116</issn><issn>1573-2568</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2018</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><recordid>eNp1kU9rFTEUxYMo9ln9AG4k4KabaW-Slz-zfAyvKhSEtvuYZu48U2Ym02Sm4Lc3w6sWRcniXpLfOZxwCHnP4JwB6IvMQHGogJlKAq8reEE2TGpRcanMS7IBpsrOmDohb3K-B4BaM_WanPBaqq3SsCHfmiW5OTwibVKYMQVHd12ZdD-2Mfs4BU-vMaOfQxxpFxO9WSZMXfDB9XSf4_TdHbCsNw-LG-KSaYN9TxuXfBjj4PJb8qpzfcZ3T_OU3F7ub5vP1dXXT1-a3VXlleBzJVrhjFclIRpVKycRtnLLuRMKpKlbwe78VnKOqJRwXLe-Fdp4g0Zi26I4JWdH2ynFhwXzbIeQfYniRiypLAemQUowdUE__oXexyWNJdxKKaYlCPNMHVyPNoxdnJPzq6ndacZrYcBAoc7_QZXT4hB8HLEL5f4PATsKfIo5J-zslMLg0g_LwK6l2mOptpRq11LtqvnwFHi5G7D9rfjVYgH4EcjlaTxgev7R_11_AihXqiI</recordid><startdate>20180601</startdate><enddate>20180601</enddate><creator>Mizumoto, T.</creator><creator>Hiyama, T.</creator><creator>Oka, S.</creator><creator>Yorita, N.</creator><creator>Kuroki, K.</creator><creator>Kurihara, M.</creator><creator>Yoshifuku, Y.</creator><creator>Sanomura, Y.</creator><creator>Urabe, Y.</creator><creator>Murakami, Y.</creator><creator>Arihiro, K.</creator><creator>Tanaka, S.</creator><creator>Chayama, K.</creator><general>Springer US</general><general>Springer</general><general>Springer Nature B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7RV</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9-</scope><scope>K9.</scope><scope>KB0</scope><scope>M0R</scope><scope>M0S</scope><scope>M1P</scope><scope>NAPCQ</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope></search><sort><creationdate>20180601</creationdate><title>Curative Criteria After Endoscopic Resection for Superficial Esophageal Squamous Cell Carcinomas</title><author>Mizumoto, T. ; Hiyama, T. ; Oka, S. ; Yorita, N. ; Kuroki, K. ; Kurihara, M. ; Yoshifuku, Y. ; Sanomura, Y. ; Urabe, Y. ; Murakami, Y. ; Arihiro, K. ; Tanaka, S. ; Chayama, K.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c632t-3d3a8c6009e8696a5e045422a360589d31bc4522ee663a27dcd378c8e85edde3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2018</creationdate><topic>Aged</topic><topic>Biochemistry</topic><topic>Carcinoma, Squamous Cell - mortality</topic><topic>Carcinoma, Squamous Cell - secondary</topic><topic>Carcinoma, Squamous Cell - surgery</topic><topic>Disease Progression</topic><topic>Disease-Free Survival</topic><topic>Endoscopy</topic><topic>Esophageal cancer</topic><topic>Esophageal Neoplasms - mortality</topic><topic>Esophageal Neoplasms - pathology</topic><topic>Esophageal Neoplasms - surgery</topic><topic>Esophageal Squamous Cell Carcinoma</topic><topic>Esophagectomy - adverse effects</topic><topic>Esophagectomy - methods</topic><topic>Esophagectomy - mortality</topic><topic>Esophagoscopy - adverse effects</topic><topic>Esophagoscopy - mortality</topic><topic>Esophagus</topic><topic>Female</topic><topic>Gastroenterology</topic><topic>Hepatology</topic><topic>Hospitals, University</topic><topic>Humans</topic><topic>Japan</topic><topic>Kaplan-Meier Estimate</topic><topic>Lymphatic Metastasis</topic><topic>Male</topic><topic>Medical prognosis</topic><topic>Medical research</topic><topic>Medicine</topic><topic>Medicine & Public Health</topic><topic>Medicine, Experimental</topic><topic>Metastasis</topic><topic>Middle Aged</topic><topic>Neoplasm Invasiveness</topic><topic>Neoplasm Recurrence, Local</topic><topic>Oncology</topic><topic>Original Article</topic><topic>Prognosis</topic><topic>Retrospective Studies</topic><topic>Risk Factors</topic><topic>Squamous cell carcinoma</topic><topic>Surgery</topic><topic>Time Factors</topic><topic>Transplant Surgery</topic><topic>Treatment Outcome</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Mizumoto, T.</creatorcontrib><creatorcontrib>Hiyama, T.</creatorcontrib><creatorcontrib>Oka, S.</creatorcontrib><creatorcontrib>Yorita, N.</creatorcontrib><creatorcontrib>Kuroki, K.</creatorcontrib><creatorcontrib>Kurihara, M.</creatorcontrib><creatorcontrib>Yoshifuku, Y.</creatorcontrib><creatorcontrib>Sanomura, Y.</creatorcontrib><creatorcontrib>Urabe, Y.</creatorcontrib><creatorcontrib>Murakami, Y.</creatorcontrib><creatorcontrib>Arihiro, K.</creatorcontrib><creatorcontrib>Tanaka, S.</creatorcontrib><creatorcontrib>Chayama, K.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Nursing & Allied Health Database</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>Consumer Health Database (Alumni Edition)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>Consumer Health Database</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Nursing & Allied Health Premium</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><jtitle>Digestive diseases and sciences</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Mizumoto, T.</au><au>Hiyama, T.</au><au>Oka, S.</au><au>Yorita, N.</au><au>Kuroki, K.</au><au>Kurihara, M.</au><au>Yoshifuku, Y.</au><au>Sanomura, Y.</au><au>Urabe, Y.</au><au>Murakami, Y.</au><au>Arihiro, K.</au><au>Tanaka, S.</au><au>Chayama, K.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Curative Criteria After Endoscopic Resection for Superficial Esophageal Squamous Cell Carcinomas</atitle><jtitle>Digestive diseases and sciences</jtitle><stitle>Dig Dis Sci</stitle><addtitle>Dig Dis Sci</addtitle><date>2018-06-01</date><risdate>2018</risdate><volume>63</volume><issue>6</issue><spage>1605</spage><epage>1612</epage><pages>1605-1612</pages><issn>0163-2116</issn><eissn>1573-2568</eissn><abstract>Background
According to the Japanese Esophageal Society (JES) guidelines, risk factors for lymph node (LN) metastasis in the muscularis mucosa (MM)/submucosa to a depth of up to 200 μm (SM1) in cases of esophageal squamous cell carcinomas (ESCCs) include the presence of lymphatic invasion (ly), venous invasion (v), infiltration pattern (INF)c, and SM1. The long-term prognoses of these patients are unclear, and there are very few reports on the validation of the curative criteria for MM/SM1 ESCCs.
Aims
To examine the long-term prognoses of these patients and the risk factors for LN metastasis of MM/SM1 ESCCs after endoscopic resection (ER).
Methods
This study included patients with MM/SM1 ESCCs who underwent ER at Hiroshima University Hospital from December 1990 to November 2016. We evaluated the clinicopathological characteristics of 98 patients and overall survival, disease-specific survival, recurrence-free survival, and recurrence rates in the e-curative and non-e-curative groups.
Results
The mean observation period was 75 months. There was no significant difference in disease-specific survival rate between the e-curative and non-e-curative groups (100 vs. 98%). There was no significant difference in disease-specific survival rates between the groups (100 vs. 98%). In contrast, the LN recurrence-free survival rate in patients with INFa, ly(−), and v(−) was significantly higher than that in patients with INFb/c, ly(+), or v(+) (100 and 87%,
P
< 0.05).
Conclusion
Contrary to the JES guidelines, our findings suggest that new criteria (MM/SM1, INFa, negative vertical margin (VM0), ly[-], and v[-]) may be associated with curative ER without additional treatment.</abstract><cop>New York</cop><pub>Springer US</pub><pmid>29564670</pmid><doi>10.1007/s10620-018-5029-0</doi><tpages>8</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
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| source | MEDLINE; Springer Nature - Complete Springer Journals |
| subjects | Aged Biochemistry Carcinoma, Squamous Cell - mortality Carcinoma, Squamous Cell - secondary Carcinoma, Squamous Cell - surgery Disease Progression Disease-Free Survival Endoscopy Esophageal cancer Esophageal Neoplasms - mortality Esophageal Neoplasms - pathology Esophageal Neoplasms - surgery Esophageal Squamous Cell Carcinoma Esophagectomy - adverse effects Esophagectomy - methods Esophagectomy - mortality Esophagoscopy - adverse effects Esophagoscopy - mortality Esophagus Female Gastroenterology Hepatology Hospitals, University Humans Japan Kaplan-Meier Estimate Lymphatic Metastasis Male Medical prognosis Medical research Medicine Medicine & Public Health Medicine, Experimental Metastasis Middle Aged Neoplasm Invasiveness Neoplasm Recurrence, Local Oncology Original Article Prognosis Retrospective Studies Risk Factors Squamous cell carcinoma Surgery Time Factors Transplant Surgery Treatment Outcome |
| title | Curative Criteria After Endoscopic Resection for Superficial Esophageal Squamous Cell Carcinomas |
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