PET Imaging Analysis of Vitamin B1 Kinetics with [11C]Thiamine and its Derivative [11C]Thiamine Tetrahydrofurfuryl Disulfide in Rats

Purpose Thiamine is an essential component of glucose metabolism and energy production. The disulfide derivative, thiamine tetrahydrofurfuryl disulfide (TTFD), is better absorbed than readily-available water-soluble thiamine salts because it does not require the rate-limiting transport system requir...

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Veröffentlicht in:	Molecular imaging and biology 2018-12, Vol.20 (6), p.1001-1007
Hauptverfasser:	Nozaki, Satoshi, Mawatari, Aya, Nakatani, Yuka, Hayashinaka, Emi, Wada, Yasuhiro, Nomura, Yukihiro, Kitayoshi, Takahito, Akimoto, Kouji, Ninomiya, Shinji, Doi, Hisashi, Watanabe, Yasuyoshi
Format:	Artikel
Sprache:	eng
Schlagworte:	Energy metabolism Glucose Glucose metabolism Heart Heart diseases Imaging Imaging techniques Kinetics Medical imaging Medicine Medicine & Public Health Metabolism Pharmacokinetics Pharmacology Positron emission Positron emission tomography Probes Radiology Rats Research Article Salts Thiamine Thin layer chromatography Tomography Vitamin B Vitamin B1
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