Metabolic pathway interruption: CRISPR/Cas9-mediated knockout of tryptophan 2,3-dioxygenase in Tribolium castaneum

[Display omitted] •CRISPR/Cas9-mediated editing of Tribolium castaneum vermilion gene.•Generation of new T. castaneum white-eyed mutant strain; vermilionICE (vICE).•First report of a CRISPR-induced eye-color mutation in beetles. The Tribolium castaneum vermilion gene encodes tryptophan 2,3-dioxygena...

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