Ovariectomy Exacerbates Apical Periodontitis in Rats with an Increase in Expression of Proinflammatory Cytokines and Matrix Metalloproteinases

The aim of this study was to evaluate the gene expression of proinflammatory cytokines, matrix metalloproteinases (MMPs), and cathepsin K in apical periodontitis (AP) and the volume of lesions in ovariectomized and sham-operated rats. Twenty 12-week-old female Wistar rats were subjected to ovariecto...

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Veröffentlicht in:Journal of endodontics 2018-05, Vol.44 (5), p.780-785
Hauptverfasser: Romualdo, Priscilla Coutinho, Lucisano, Marília P., Paula-Silva, Francisco Wanderley G., Leoni, Graziela B., Sousa-Neto, Manoel D., Silva, Raquel Assed B., Silva, Lea Assed B., Nelson-Filho, Paulo
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Sprache:eng
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