Moderate Alcohol Consumption Is Associated with Reduced Pain and Fibromyalgia Symptoms in Chronic Pain Patients

Abstract Objective Moderate alcohol consumption has been associated with improved health outcomes including reduced risk of heart disease; however, less is known regarding alcohol’s effects on chronic pain. The aim of this study was to assess associations between pain, fibromyalgia symptoms, and mod...

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Veröffentlicht in:Pain medicine (Malden, Mass.) Mass.), 2018-12, Vol.19 (12), p.2515-2527
Hauptverfasser: Scott, J Ryan, Hassett, Afton L, Schrepf, Andrew D, Brummett, Chad M, Harris, Richard E, Clauw, Daniel J, Harte, Steven E
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container_end_page 2527
container_issue 12
container_start_page 2515
container_title Pain medicine (Malden, Mass.)
container_volume 19
creator Scott, J Ryan
Hassett, Afton L
Schrepf, Andrew D
Brummett, Chad M
Harris, Richard E
Clauw, Daniel J
Harte, Steven E
description Abstract Objective Moderate alcohol consumption has been associated with improved health outcomes including reduced risk of heart disease; however, less is known regarding alcohol’s effects on chronic pain. The aim of this study was to assess associations between pain, fibromyalgia symptoms, and moderate alcohol use in a large chronic pain sample. Methods A total of 2,583 new chronic pain patients presenting at a university pain clinic reported alcohol use and completed validated measures; 592 (23%) patients reported drinking, with 502 (85%) classified as moderate drinkers (females ≤7 and males ≤14 drinks/wk). General linear models (GLM) assessed the effects of moderate drinking on pain and symptom outcomes. The sample was stratified by gender and fibromyalgia (FM) status in secondary analyses. Results Moderate alcohol users reported significantly lower FM symptoms (widespread pain and symptom severity), pain severity, interference, anxiety, depression, and catastrophizing, and they reported higher physical function. Similar findings were observed in gender-stratified analysis, minus associations with FM symptom severity in females and anxiety in males. In patients meeting FM criteria, moderate drinking was associated with lower pain severity, interference, and depression, and higher physical function. Results in non-FM patients were similar to the total sample. Conclusions Moderate alcohol consumption in chronic pain patients was associated with decreased pain severity and interference, fewer painful body areas, lower somatic and mood symptoms, and increased physical function. A similar effect was observed in non-FM patients, but to a lesser extent in FM patients, suggesting chronic pain patients with less centralized forms of pain may benefit most from moderate alcohol consumption.
doi_str_mv 10.1093/pm/pny032
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The aim of this study was to assess associations between pain, fibromyalgia symptoms, and moderate alcohol use in a large chronic pain sample. Methods A total of 2,583 new chronic pain patients presenting at a university pain clinic reported alcohol use and completed validated measures; 592 (23%) patients reported drinking, with 502 (85%) classified as moderate drinkers (females ≤7 and males ≤14 drinks/wk). General linear models (GLM) assessed the effects of moderate drinking on pain and symptom outcomes. The sample was stratified by gender and fibromyalgia (FM) status in secondary analyses. Results Moderate alcohol users reported significantly lower FM symptoms (widespread pain and symptom severity), pain severity, interference, anxiety, depression, and catastrophizing, and they reported higher physical function. Similar findings were observed in gender-stratified analysis, minus associations with FM symptom severity in females and anxiety in males. In patients meeting FM criteria, moderate drinking was associated with lower pain severity, interference, and depression, and higher physical function. Results in non-FM patients were similar to the total sample. Conclusions Moderate alcohol consumption in chronic pain patients was associated with decreased pain severity and interference, fewer painful body areas, lower somatic and mood symptoms, and increased physical function. A similar effect was observed in non-FM patients, but to a lesser extent in FM patients, suggesting chronic pain patients with less centralized forms of pain may benefit most from moderate alcohol consumption.</description><identifier>ISSN: 1526-2375</identifier><identifier>EISSN: 1526-4637</identifier><identifier>DOI: 10.1093/pm/pny032</identifier><identifier>PMID: 29546348</identifier><language>eng</language><publisher>England: Oxford University Press</publisher><subject>Adult ; Aged ; Aged, 80 and over ; Alcohol Drinking - adverse effects ; Alcohol use ; Alcoholic beverages ; Anxiety ; Anxiety - diagnosis ; Anxiety - etiology ; Anxiety Disorders - etiology ; Chronic pain ; Chronic Pain - etiology ; Coronary artery disease ; Depression - diagnosis ; Depressive Disorder - etiology ; Drinking behavior ; Female ; Fibromyalgia ; Fibromyalgia - diagnosis ; Fibromyalgia - etiology ; Heart diseases ; Humans ; Male ; Mental depression ; Middle Aged ; Mood ; Pain ; Pain management ; Pain Measurement - methods ; Severity of Illness Index ; Substance use disorder</subject><ispartof>Pain medicine (Malden, Mass.), 2018-12, Vol.19 (12), p.2515-2527</ispartof><rights>2018 American Academy of Pain Medicine. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com 2018</rights><rights>2018 American Academy of Pain Medicine. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c342t-87d57d6054b3873208cb6c1179d5ed6af501f4f94d0f00c6a528206c6f0a55233</citedby><cites>FETCH-LOGICAL-c342t-87d57d6054b3873208cb6c1179d5ed6af501f4f94d0f00c6a528206c6f0a55233</cites><orcidid>0000-0002-4900-0891</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,1578,27903,27904</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/29546348$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Scott, J Ryan</creatorcontrib><creatorcontrib>Hassett, Afton L</creatorcontrib><creatorcontrib>Schrepf, Andrew D</creatorcontrib><creatorcontrib>Brummett, Chad M</creatorcontrib><creatorcontrib>Harris, Richard E</creatorcontrib><creatorcontrib>Clauw, Daniel J</creatorcontrib><creatorcontrib>Harte, Steven E</creatorcontrib><title>Moderate Alcohol Consumption Is Associated with Reduced Pain and Fibromyalgia Symptoms in Chronic Pain Patients</title><title>Pain medicine (Malden, Mass.)</title><addtitle>Pain Med</addtitle><description>Abstract Objective Moderate alcohol consumption has been associated with improved health outcomes including reduced risk of heart disease; however, less is known regarding alcohol’s effects on chronic pain. The aim of this study was to assess associations between pain, fibromyalgia symptoms, and moderate alcohol use in a large chronic pain sample. Methods A total of 2,583 new chronic pain patients presenting at a university pain clinic reported alcohol use and completed validated measures; 592 (23%) patients reported drinking, with 502 (85%) classified as moderate drinkers (females ≤7 and males ≤14 drinks/wk). General linear models (GLM) assessed the effects of moderate drinking on pain and symptom outcomes. The sample was stratified by gender and fibromyalgia (FM) status in secondary analyses. Results Moderate alcohol users reported significantly lower FM symptoms (widespread pain and symptom severity), pain severity, interference, anxiety, depression, and catastrophizing, and they reported higher physical function. Similar findings were observed in gender-stratified analysis, minus associations with FM symptom severity in females and anxiety in males. In patients meeting FM criteria, moderate drinking was associated with lower pain severity, interference, and depression, and higher physical function. Results in non-FM patients were similar to the total sample. Conclusions Moderate alcohol consumption in chronic pain patients was associated with decreased pain severity and interference, fewer painful body areas, lower somatic and mood symptoms, and increased physical function. 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Hassett, Afton L ; Schrepf, Andrew D ; Brummett, Chad M ; Harris, Richard E ; Clauw, Daniel J ; Harte, Steven E</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c342t-87d57d6054b3873208cb6c1179d5ed6af501f4f94d0f00c6a528206c6f0a55233</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2018</creationdate><topic>Adult</topic><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Alcohol Drinking - adverse effects</topic><topic>Alcohol use</topic><topic>Alcoholic beverages</topic><topic>Anxiety</topic><topic>Anxiety - diagnosis</topic><topic>Anxiety - etiology</topic><topic>Anxiety Disorders - etiology</topic><topic>Chronic pain</topic><topic>Chronic Pain - etiology</topic><topic>Coronary artery disease</topic><topic>Depression - diagnosis</topic><topic>Depressive Disorder - etiology</topic><topic>Drinking behavior</topic><topic>Female</topic><topic>Fibromyalgia</topic><topic>Fibromyalgia - diagnosis</topic><topic>Fibromyalgia - etiology</topic><topic>Heart diseases</topic><topic>Humans</topic><topic>Male</topic><topic>Mental depression</topic><topic>Middle Aged</topic><topic>Mood</topic><topic>Pain</topic><topic>Pain management</topic><topic>Pain Measurement - methods</topic><topic>Severity of Illness Index</topic><topic>Substance use disorder</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Scott, J Ryan</creatorcontrib><creatorcontrib>Hassett, Afton L</creatorcontrib><creatorcontrib>Schrepf, Andrew D</creatorcontrib><creatorcontrib>Brummett, Chad M</creatorcontrib><creatorcontrib>Harris, Richard E</creatorcontrib><creatorcontrib>Clauw, Daniel J</creatorcontrib><creatorcontrib>Harte, Steven E</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Nursing &amp; 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however, less is known regarding alcohol’s effects on chronic pain. The aim of this study was to assess associations between pain, fibromyalgia symptoms, and moderate alcohol use in a large chronic pain sample. Methods A total of 2,583 new chronic pain patients presenting at a university pain clinic reported alcohol use and completed validated measures; 592 (23%) patients reported drinking, with 502 (85%) classified as moderate drinkers (females ≤7 and males ≤14 drinks/wk). General linear models (GLM) assessed the effects of moderate drinking on pain and symptom outcomes. The sample was stratified by gender and fibromyalgia (FM) status in secondary analyses. Results Moderate alcohol users reported significantly lower FM symptoms (widespread pain and symptom severity), pain severity, interference, anxiety, depression, and catastrophizing, and they reported higher physical function. Similar findings were observed in gender-stratified analysis, minus associations with FM symptom severity in females and anxiety in males. In patients meeting FM criteria, moderate drinking was associated with lower pain severity, interference, and depression, and higher physical function. Results in non-FM patients were similar to the total sample. Conclusions Moderate alcohol consumption in chronic pain patients was associated with decreased pain severity and interference, fewer painful body areas, lower somatic and mood symptoms, and increased physical function. A similar effect was observed in non-FM patients, but to a lesser extent in FM patients, suggesting chronic pain patients with less centralized forms of pain may benefit most from moderate alcohol consumption.</abstract><cop>England</cop><pub>Oxford University Press</pub><pmid>29546348</pmid><doi>10.1093/pm/pny032</doi><tpages>13</tpages><orcidid>https://orcid.org/0000-0002-4900-0891</orcidid></addata></record>
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subjects Adult
Aged
Aged, 80 and over
Alcohol Drinking - adverse effects
Alcohol use
Alcoholic beverages
Anxiety
Anxiety - diagnosis
Anxiety - etiology
Anxiety Disorders - etiology
Chronic pain
Chronic Pain - etiology
Coronary artery disease
Depression - diagnosis
Depressive Disorder - etiology
Drinking behavior
Female
Fibromyalgia
Fibromyalgia - diagnosis
Fibromyalgia - etiology
Heart diseases
Humans
Male
Mental depression
Middle Aged
Mood
Pain
Pain management
Pain Measurement - methods
Severity of Illness Index
Substance use disorder
title Moderate Alcohol Consumption Is Associated with Reduced Pain and Fibromyalgia Symptoms in Chronic Pain Patients
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