Cardiac unloading by LVAD support differentially influences components of the cGMP–PKG signaling pathway in ischemic and dilated cardiomyopathy

Implantation of left ventricular assist devices (LVADs) as bridge to transplant in end-stage heart failure allows for analyzing reverse remodeling processes of the supported heart. Whether this therapy influences the cGMP–PKG signaling pathway, which is currently under thorough investigation for dev...

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Veröffentlicht in:	Heart and vessels 2018-08, Vol.33 (8), p.948-957
Hauptverfasser:	Persoon, Sven, Paulus, Michael, Hirt, Stephan, Jungbauer, Carsten, Dietl, Alexander, Luchner, Andreas, Schmid, Christof, Maier, Lars S., Birner, Christoph
Format:	Artikel
Sprache:	eng
Schlagworte:	Biomedical Engineering and Bioengineering Bridge failure Cardiac Surgery Cardiology Cardiomyopathy Cyclic GMP Dilated cardiomyopathy Enzyme-linked immunosorbent assay Etiology Guanylate cyclase Heart Heart diseases Heart failure Heart transplantation Implantation Ischemia Kinases Mechanical unloading Medicine Medicine & Public Health Neprilysin Original Article Patients Polymerase chain reaction Protein kinase Protein kinase G Signal transduction Signaling Therapeutic applications Therapy Transplantation Transplants & implants Vascular Surgery Ventricle Ventricular assist devices
Online-Zugang:	Volltext
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