Human umbilical cord blood (HUCB) cells for central nervous system repair
Cellular therapy is a compelling and potential treatment for certain neurological and neurodegenerative diseases as well as a viable treatment for acute injury to the spinal cord and brain. The hematopoietic system offers alternative sources for stem cells compared to those of fetal or embryonic ori...
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| Veröffentlicht in: | Neurotoxicity research 2003, Vol.5 (5), p.355-368 |
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| container_end_page | 368 |
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| container_title | Neurotoxicity research |
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| creator | Newman, Mary B Davis, Cyndy D Kuzmin-Nichols, Nicole Sanberg, Paul R |
| description | Cellular therapy is a compelling and potential treatment for certain neurological and neurodegenerative diseases as well as a viable treatment for acute injury to the spinal cord and brain. The hematopoietic system offers alternative sources for stem cells compared to those of fetal or embryonic origin. Bone marrow stromal and umbilical cord cells have been used in pre-clinical models of brain injury, directed to differentiate into neural phenotypes, and have been related to functional recovery after engraftment in central nervous system (CNS) injury models. This paper reviews the advantages, utilization and progress of human umbilical cord blood (HUCB) cells in the neural cell transplantation and repair field. |
| doi_str_mv | 10.1007/bf03033155 |
| format | Article |
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| fulltext | fulltext |
| identifier | ISSN: 1029-8428 |
| ispartof | Neurotoxicity research, 2003, Vol.5 (5), p.355-368 |
| issn | 1029-8428 1476-3524 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_20142059 |
| source | MEDLINE; Springer Nature - Complete Springer Journals |
| subjects | Animals Central Nervous System Diseases - therapy Cord Blood Stem Cell Transplantation Humans Infant, Newborn Neurons - physiology Phenotype Rats |
| title | Human umbilical cord blood (HUCB) cells for central nervous system repair |
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