Glutathione-Depleting Gold Nanoclusters for Enhanced Cancer Radiotherapy through Synergistic External and Internal Regulations

The therapeutic performance of cancer radiotherapy is often limited by the overexpression of glutathione (GSH) in tumors and low radiation sensitivity of cancerous cells. To address these issues, the facilely prepared histidine-capped gold nanoclusters (Au NCs@His) were adopted as a radiosensitizer...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	ACS applied materials & interfaces 2018-04, Vol.10 (13), p.10601-10606
Hauptverfasser:	Zhang, Xiaodong, Chen, Xiaokai, Jiang, Yao-Wen, Ma, Ningning, Xia, Liu-Yuan, Cheng, Xiaotong, Jia, Hao-Ran, Liu, Peidang, Gu, Ning, Chen, Zhan, Wu, Fu-Gen
Format:	Artikel
Sprache:	eng
Schlagworte:	Glutathione - chemistry Gold Humans Metal Nanoparticles Neoplasms Radiation-Sensitizing Agents
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!