2-Aryl benzimidazoles: Synthesis, In vitro α-amylase inhibitory activity, and molecular docking study

Despite of many diverse biological activities exhibited by benzimidazole scaffold, it is rarely explored for the α-amylase inhibitory activity. For that purpose, 2-aryl benzimidazole derivatives 1–45 were synthesized and screened for in vitro α-amylase inhibitory activity. Structures of all syntheti...

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Veröffentlicht in:	European journal of medicinal chemistry 2018-04, Vol.150, p.248-260
Hauptverfasser:	Adegboye, Akande Akinsola, Khan, Khalid Mohammed, Salar, Uzma, Aboaba, Sherifat Adeyinka, Kanwal, Chigurupati, Sridevi, Fatima, Itrat, Taha, Mohammad, Wadood, Abdul, Mohammad, Jahidul Isalm, Khan, Huma, Perveen, Shahnaz
Format:	Artikel
Sprache:	eng
Schlagworte:	Benzimidazole In silico In vitro Structure-activity relationship (SAR) α-Amylase
Online-Zugang:	Volltext
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