The role of interleukin-33 in pathogenesis of bronchial asthma. New experimental data

Interleukin-33 (IL-33) belongs to the IL-1 cytokine family and plays an important role in modulating immune system by inducing Th2 immune response via the ST2 membrane receptor. Epithelial cells are the major producers of IL-33. However, IL-33 is also secreted by other cells, e.g., bone marrow cells...

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Veröffentlicht in:	Biochemistry (Moscow) 2018, Vol.83 (1), p.13-25
Hauptverfasser:	Khaitov, M. R., Gaisina, A. R., Shilovskiy, I. P., Smirnov, V. V., Ramenskaia, G. V., Nikonova, A. A., Khaitov, R. M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animal models Asthma Biochemistry Biomedical and Life Sciences Biomedicine Bioorganic Chemistry Bone marrow Cytokines Data processing Dendritic cells Eosinophils Epithelial cells Health aspects Helper cells Immune response Immune system Inflammatory diseases Interleukin 1 Interleukins Leukocytes (basophilic) Leukocytes (eosinophilic) Life Sciences Lymphocytes T Macrophages Mast cells Microbiology Monoclonal antibodies Pathogenesis Physiological aspects Review Rodents Transgenic mice
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