Clinical features of Enterococcus faecium meningitis in children

To summarize the clinical features of Enterococcus faecium meningitis in children. The clinical data of nine children with Enterococcus faecium meningitis were analyzed. In all the nine children, Enterococcus faecium was isolated from blood, cerebrospinal fluid, or peripherally inserted central cath...

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Veröffentlicht in:Zhongguo dang dai er ke za zhi 2018-03, Vol.20 (3), p.200
Hauptverfasser: Wang, Li-Yuan, Cai, Xiao-Tang, Wang, Zhi-Ling, Liu, Shun-Li, Xie, Yong-Mei, Zhou, Hui
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container_issue 3
container_start_page 200
container_title Zhongguo dang dai er ke za zhi
container_volume 20
creator Wang, Li-Yuan
Cai, Xiao-Tang
Wang, Zhi-Ling
Liu, Shun-Li
Xie, Yong-Mei
Zhou, Hui
description To summarize the clinical features of Enterococcus faecium meningitis in children. The clinical data of nine children with Enterococcus faecium meningitis were analyzed. In all the nine children, Enterococcus faecium was isolated from blood, cerebrospinal fluid, or peripherally inserted central catheters; 6 (67%) patients were neonates, 2 (22%) patients were younger than 6 months, and 1 (11%) patient was three years and four months of age. In those patients, 56% had high-risk factors before onset, which included intestinal infection, resettlement of drainage tube after surgery for hydrocephalus, skull fracture, perinatal maternal infection history, and catheter-related infection. The main symptoms were fever and poor response. In those patients, 22% had seizures; no child had meningeal irritation sign or disturbance of consciousness. The white blood cell count and level of C-reactive protein were normal or increased; the nucleated cell count in cerebrospinal fluid was normal or mildly elevated; the protein le
doi_str_mv 10.7499/j.issn.1008-8830.2018.03.007
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The clinical data of nine children with Enterococcus faecium meningitis were analyzed. In all the nine children, Enterococcus faecium was isolated from blood, cerebrospinal fluid, or peripherally inserted central catheters; 6 (67%) patients were neonates, 2 (22%) patients were younger than 6 months, and 1 (11%) patient was three years and four months of age. In those patients, 56% had high-risk factors before onset, which included intestinal infection, resettlement of drainage tube after surgery for hydrocephalus, skull fracture, perinatal maternal infection history, and catheter-related infection. The main symptoms were fever and poor response. In those patients, 22% had seizures; no child had meningeal irritation sign or disturbance of consciousness. 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The clinical data of nine children with Enterococcus faecium meningitis were analyzed. In all the nine children, Enterococcus faecium was isolated from blood, cerebrospinal fluid, or peripherally inserted central catheters; 6 (67%) patients were neonates, 2 (22%) patients were younger than 6 months, and 1 (11%) patient was three years and four months of age. In those patients, 56% had high-risk factors before onset, which included intestinal infection, resettlement of drainage tube after surgery for hydrocephalus, skull fracture, perinatal maternal infection history, and catheter-related infection. The main symptoms were fever and poor response. In those patients, 22% had seizures; no child had meningeal irritation sign or disturbance of consciousness. 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The clinical data of nine children with Enterococcus faecium meningitis were analyzed. In all the nine children, Enterococcus faecium was isolated from blood, cerebrospinal fluid, or peripherally inserted central catheters; 6 (67%) patients were neonates, 2 (22%) patients were younger than 6 months, and 1 (11%) patient was three years and four months of age. In those patients, 56% had high-risk factors before onset, which included intestinal infection, resettlement of drainage tube after surgery for hydrocephalus, skull fracture, perinatal maternal infection history, and catheter-related infection. The main symptoms were fever and poor response. In those patients, 22% had seizures; no child had meningeal irritation sign or disturbance of consciousness. 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subjects C-Reactive Protein - analysis
Enterococcus faecium - drug effects
Female
Gram-Positive Bacterial Infections - blood
Gram-Positive Bacterial Infections - diagnosis
Gram-Positive Bacterial Infections - drug therapy
Gram-Positive Bacterial Infections - etiology
Humans
Infant
Infant, Newborn
Male
Meningitis, Bacterial - blood
Meningitis, Bacterial - diagnosis
Meningitis, Bacterial - drug therapy
Meningitis, Bacterial - etiology
Vancomycin - pharmacology
title Clinical features of Enterococcus faecium meningitis in children
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