Hemoadsorption of high-mobility-group box 1 using a porous polymethylmethacrylate fiber in a swine acute liver failure model

Background: High-mobility-group box chromosomal protein 1 has been identified as an important mediator of various kinds of acute and chronic inflammation. In this study, we aimed to develop a column that effectively adsorbs high-mobility-group box chromosomal protein 1 by altering the pore size of t...

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Veröffentlicht in:	International journal of artificial organs 2018-04, Vol.41 (4), p.190-200
Hauptverfasser:	Amemiya, Ryusuke, Shinoda, Masahiro, Yamada, Masayuki, Ueno, Yoshiyuki, Shimada, Kaoru, Fujieda, Hiroaki, Yagi, Hiroshi, Mizota, Takamasa, Nishiyama, Ryo, Oshima, Go, Yamada, Shingo, Matsubara, Kentaro, Abe, Yuta, Hibi, Taizo, Kitago, Minoru, Obara, Hideaki, Itano, Osamu, Kitagawa, Yuko
Format:	Artikel
Sprache:	eng
Schlagworte:	Adsorption Hemoperfusion In vitro methods and tests In vivo methods and tests Incubation Liver Liver failure Livestock Mobility Polymethylmethacrylate Pore size Porosity Proteins Swine
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