Development of N‐acetylneuraminic acid responsive biosensors based on the transcriptional regulator NanR

Transcriptional biosensors have various applications in metabolic engineering, including dynamic pathway control and high‐throughput screening of combinatorial strain libraries. Previously, various biosensors have been created from naturally occurring transcription factors (TFs), largely relying on...

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Veröffentlicht in:	Biotechnology and bioengineering 2018-07, Vol.115 (7), p.1855-1865
Hauptverfasser:	Peters, Gert, De Paepe, Brecht, De Wannemaeker, Lien, Duchi, Dries, Maertens, Jo, Lammertyn, Jeroen, De Mey, Marjan
Format:	Artikel
Sprache:	eng
Schlagworte:	Acids Binding sites Biosensors Combinatorial analysis Design engineering Metabolic engineering NanR N‐acetylneuraminic acid Sugar synthetic biology Transcription factors transcriptional biosensor
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