Re-admissions treble the risk of late mortality after primary total hip arthroplasty

Background Following a total hip arthroplasty (THA), early hospital re-admission rates of 3–11% are considered as ‘acceptable’ in terms of medical care cost policies. Surprisingly, the impact of re-admissions on mortality has not been priorly portrayed. Therefore, we sought to determine the mortalit...

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Veröffentlicht in:International orthopaedics 2018-09, Vol.42 (9), p.2015-2023
Hauptverfasser: Slullitel, Pablo A., Estefan, Martín, Ramírez-Serrudo, Wilber M., Comba, Fernando M., Zanotti, Gerardo, Piccaluga, Francisco, Buttaro, Martín A.
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container_end_page 2023
container_issue 9
container_start_page 2015
container_title International orthopaedics
container_volume 42
creator Slullitel, Pablo A.
Estefan, Martín
Ramírez-Serrudo, Wilber M.
Comba, Fernando M.
Zanotti, Gerardo
Piccaluga, Francisco
Buttaro, Martín A.
description Background Following a total hip arthroplasty (THA), early hospital re-admission rates of 3–11% are considered as ‘acceptable’ in terms of medical care cost policies. Surprisingly, the impact of re-admissions on mortality has not been priorly portrayed. Therefore, we sought to determine the mortality rate after 90-day re-admissions following a THA in a series of patients from a captive medical care program. Patients and methods We prospectively analysed 90-day readmissions of 815 unilateral, elective THA patients operated upon between 2010 and 2014 whose medical care was the one offered by our institution. We stratified our sample into readmitted and non-readmitted cohorts. Through a Cox proportional hazards model, we compared demographic characteristics, clinical comorbidities, surgical outcomes and laboratory values between both groups in order to determine association with early and late mortality. Results We found 37 (4.53%) re-admissions at a median time of 40.44 days (IQR 17.46–60.69). Factors associated with re-admission were hospital stay ( p  = 0.00); surgical time ( p  = 0.01); chronic renal insufficiency ( p  = 0.03); ASA class 4 ( p  = 0.00); morbid obesity ( p  = 0.006); diabetes ( p  = 0.04) and a high Charlson index ( p  = 0.00). Overall mortality rate of the series was 3.31% (27/815). Median time to mortality was 455.5 days (IQR 297.58–1170.65). One-third (11/37) of the re-admitted patients died, being sepsis non-related to the THA the most common cause of death. After adjusting for confounders, 90-day re-admissions remained associated with mortality with an adjusted HR of 3.14 (CI95% 1.05–9.36, p  = 0.04). Conclusions Unplanned re-admissions were an independent risk factor for future mortality, increasing three times the risk of mortality.
doi_str_mv 10.1007/s00264-018-3876-0
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Surprisingly, the impact of re-admissions on mortality has not been priorly portrayed. Therefore, we sought to determine the mortality rate after 90-day re-admissions following a THA in a series of patients from a captive medical care program. Patients and methods We prospectively analysed 90-day readmissions of 815 unilateral, elective THA patients operated upon between 2010 and 2014 whose medical care was the one offered by our institution. We stratified our sample into readmitted and non-readmitted cohorts. Through a Cox proportional hazards model, we compared demographic characteristics, clinical comorbidities, surgical outcomes and laboratory values between both groups in order to determine association with early and late mortality. Results We found 37 (4.53%) re-admissions at a median time of 40.44 days (IQR 17.46–60.69). Factors associated with re-admission were hospital stay ( p  = 0.00); surgical time ( p  = 0.01); chronic renal insufficiency ( p  = 0.03); ASA class 4 ( p  = 0.00); morbid obesity ( p  = 0.006); diabetes ( p  = 0.04) and a high Charlson index ( p  = 0.00). Overall mortality rate of the series was 3.31% (27/815). Median time to mortality was 455.5 days (IQR 297.58–1170.65). One-third (11/37) of the re-admitted patients died, being sepsis non-related to the THA the most common cause of death. After adjusting for confounders, 90-day re-admissions remained associated with mortality with an adjusted HR of 3.14 (CI95% 1.05–9.36, p  = 0.04). 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Surprisingly, the impact of re-admissions on mortality has not been priorly portrayed. Therefore, we sought to determine the mortality rate after 90-day re-admissions following a THA in a series of patients from a captive medical care program. Patients and methods We prospectively analysed 90-day readmissions of 815 unilateral, elective THA patients operated upon between 2010 and 2014 whose medical care was the one offered by our institution. We stratified our sample into readmitted and non-readmitted cohorts. Through a Cox proportional hazards model, we compared demographic characteristics, clinical comorbidities, surgical outcomes and laboratory values between both groups in order to determine association with early and late mortality. Results We found 37 (4.53%) re-admissions at a median time of 40.44 days (IQR 17.46–60.69). Factors associated with re-admission were hospital stay ( p  = 0.00); surgical time ( p  = 0.01); chronic renal insufficiency ( p  = 0.03); ASA class 4 ( p  = 0.00); morbid obesity ( p  = 0.006); diabetes ( p  = 0.04) and a high Charlson index ( p  = 0.00). Overall mortality rate of the series was 3.31% (27/815). Median time to mortality was 455.5 days (IQR 297.58–1170.65). One-third (11/37) of the re-admitted patients died, being sepsis non-related to the THA the most common cause of death. After adjusting for confounders, 90-day re-admissions remained associated with mortality with an adjusted HR of 3.14 (CI95% 1.05–9.36, p  = 0.04). 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Surprisingly, the impact of re-admissions on mortality has not been priorly portrayed. Therefore, we sought to determine the mortality rate after 90-day re-admissions following a THA in a series of patients from a captive medical care program. Patients and methods We prospectively analysed 90-day readmissions of 815 unilateral, elective THA patients operated upon between 2010 and 2014 whose medical care was the one offered by our institution. We stratified our sample into readmitted and non-readmitted cohorts. Through a Cox proportional hazards model, we compared demographic characteristics, clinical comorbidities, surgical outcomes and laboratory values between both groups in order to determine association with early and late mortality. Results We found 37 (4.53%) re-admissions at a median time of 40.44 days (IQR 17.46–60.69). Factors associated with re-admission were hospital stay ( p  = 0.00); surgical time ( p  = 0.01); chronic renal insufficiency ( p  = 0.03); ASA class 4 ( p  = 0.00); morbid obesity ( p  = 0.006); diabetes ( p  = 0.04) and a high Charlson index ( p  = 0.00). Overall mortality rate of the series was 3.31% (27/815). Median time to mortality was 455.5 days (IQR 297.58–1170.65). One-third (11/37) of the re-admitted patients died, being sepsis non-related to the THA the most common cause of death. After adjusting for confounders, 90-day re-admissions remained associated with mortality with an adjusted HR of 3.14 (CI95% 1.05–9.36, p  = 0.04). Conclusions Unplanned re-admissions were an independent risk factor for future mortality, increasing three times the risk of mortality.</abstract><cop>Berlin/Heidelberg</cop><pub>Springer Berlin Heidelberg</pub><pmid>29525914</pmid><doi>10.1007/s00264-018-3876-0</doi><tpages>9</tpages></addata></record>
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source Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; SpringerNature Journals
subjects Medicine
Medicine & Public Health
Original Paper
Orthopedics
title Re-admissions treble the risk of late mortality after primary total hip arthroplasty
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