Cytochalasin E increased the sensitivity of human lung cancer A549 cells to bortezomib via inhibition of autophagy

Cancer cells enhance autophagic activity as a survival measure against metabolic and therapeutic stresses. The inhibition of autophagy may represent a valuable sensitizing target for cancer treatment. Recently, we examined the ability of various cytochalasins to inhibit autophagy and demonstrated th...

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Veröffentlicht in:	Biochemical and biophysical research communications 2018-04, Vol.498 (3), p.603-608
Hauptverfasser:	Takanezawa, Yasukazu, Nakamura, Ryosuke, Kojima, Yuka, Sone, Yuka, Uraguchi, Shimpei, Kiyono, Masako
Format:	Artikel
Sprache:	eng
Schlagworte:	Autophagy Bortezomib Cytochalasin E Human lung cancer
Online-Zugang:	Volltext
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