Innovative material containing the natural product curcumin, with enhanced antimicrobial properties for active packaging
Curcumin (Curc) reacts with zinc di‑iodine (ZnI2) in 2:1molar ratio in the presence of an excess of a base triethylamine ((CH3CH2)3N) in methanol (CH3OH) solution towards the amorphous solid material of formula [ZnI2(Curc)2] (1). The complex was characterized by melting point (m.p.), Fourier Transfo...
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| Veröffentlicht in: | Materials Science & Engineering C 2018-03, Vol.84, p.118-122 |
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| creator | Papadimitriou, A. Ketikidis, I. Stathopoulou, M-E.K. Banti, C.N. Papachristodoulou, C. Zoumpoulakis, L. Agathopoulos, S. Vagenas, G.V. Hadjikakou, S.K. |
| description | Curcumin (Curc) reacts with zinc di‑iodine (ZnI2) in 2:1molar ratio in the presence of an excess of a base triethylamine ((CH3CH2)3N) in methanol (CH3OH) solution towards the amorphous solid material of formula [ZnI2(Curc)2] (1). The complex was characterized by melting point (m.p.), Fourier Transform-Infra Red (FT-IR) and Nuclear Magnetic Resonance of hydrogen nucleus (1H NMR) spectroscopy. The formula of 1 was determined by X-ray fluorescence (XRF) analysis. The retention of the structure in solution was confirmed by 1H NMR spectroscopy.
The antimicrobial activity of the complex has been studied against the bacteria Pseudomonas aeruginosa (PAO1). The Minimum Inhibitory Concentrations (MIC) of the compounds 1 and Curc against P. aeruginosa (PAO1) are: 71.3μΜ (75.3μg/mL) for [ZnI2(Curc)2] and 339μM (125μg/mL) for Curc, respectively. Moreover, the antimicrobial activity of the new material which was diffused in polystyrene against biofilm formed by PAO1 was also calculated.
The amorphous solid material of formula [ZnI2(Curc)2] (1) (Curc=curcumin) was synthesized and characterized. The complex was characterized by m.p., FT-IR and 1H NMR spectroscopy. The antimicrobial activity of the complex and its polystyrene@[ZnI2(Curc)2] have been studied against the bacteria Pseudomonas aeuroginosa. [Display omitted]
•Active packaging•Zinc curcumin materials•Antimicrobial activity |
| doi_str_mv | 10.1016/j.msec.2017.11.041 |
| format | Article |
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The antimicrobial activity of the complex has been studied against the bacteria Pseudomonas aeruginosa (PAO1). The Minimum Inhibitory Concentrations (MIC) of the compounds 1 and Curc against P. aeruginosa (PAO1) are: 71.3μΜ (75.3μg/mL) for [ZnI2(Curc)2] and 339μM (125μg/mL) for Curc, respectively. Moreover, the antimicrobial activity of the new material which was diffused in polystyrene against biofilm formed by PAO1 was also calculated.
The amorphous solid material of formula [ZnI2(Curc)2] (1) (Curc=curcumin) was synthesized and characterized. The complex was characterized by m.p., FT-IR and 1H NMR spectroscopy. The antimicrobial activity of the complex and its polystyrene@[ZnI2(Curc)2] have been studied against the bacteria Pseudomonas aeuroginosa. [Display omitted]
•Active packaging•Zinc curcumin materials•Antimicrobial activity</description><identifier>ISSN: 0928-4931</identifier><identifier>EISSN: 1873-0191</identifier><identifier>DOI: 10.1016/j.msec.2017.11.041</identifier><identifier>PMID: 29519419</identifier><language>eng</language><publisher>Netherlands: Elsevier B.V</publisher><subject>Active packaging materials ; Amorphous materials ; Anti-Infective Agents - chemistry ; Anti-Infective Agents - pharmacology ; Antiinfectives and antibacterials ; Antimicrobial activity ; Antimicrobial materials ; Biofilms ; Biological inorganic chemistry ; Biological Products - chemistry ; Biological Products - pharmacology ; Coordination Complexes - chemical synthesis ; Coordination Complexes - chemistry ; Coordination Complexes - pharmacology ; Curcumin ; Curcumin - chemistry ; Curcumin - pharmacology ; Curcumine ; Drug Compounding ; Fluorescence ; Fourier transforms ; Innovations ; Iodine ; Magnetic Resonance Spectroscopy ; Materials science ; Melting point ; Melting points ; Microbial Sensitivity Tests ; Minimum inhibitory concentration ; Natural products ; NMR ; NMR spectroscopy ; Nuclear magnetic resonance ; Packaging ; Polystyrene ; Polystyrene resins ; Polystyrenes - chemistry ; Pseudomonas aeruginosa ; Pseudomonas aeruginosa - drug effects ; Spectroscopy ; Spectroscopy, Fourier Transform Infrared ; Studies ; Triethylamine ; X ray fluorescence analysis ; X-Ray Diffraction ; X-ray fluorescence ; Zinc ; Zinc - chemistry</subject><ispartof>Materials Science & Engineering C, 2018-03, Vol.84, p.118-122</ispartof><rights>2017 Elsevier B.V.</rights><rights>Copyright © 2017 Elsevier B.V. All rights reserved.</rights><rights>Copyright Elsevier BV Mar 1, 2018</rights><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c421t-52fc244223e7d3ec5c445596fa9ac38eb73dad838865ad528ddc07b35b2ab3703</citedby><cites>FETCH-LOGICAL-c421t-52fc244223e7d3ec5c445596fa9ac38eb73dad838865ad528ddc07b35b2ab3703</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/S0928493117317939$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,776,780,3537,27901,27902,65306</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/29519419$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Papadimitriou, A.</creatorcontrib><creatorcontrib>Ketikidis, I.</creatorcontrib><creatorcontrib>Stathopoulou, M-E.K.</creatorcontrib><creatorcontrib>Banti, C.N.</creatorcontrib><creatorcontrib>Papachristodoulou, C.</creatorcontrib><creatorcontrib>Zoumpoulakis, L.</creatorcontrib><creatorcontrib>Agathopoulos, S.</creatorcontrib><creatorcontrib>Vagenas, G.V.</creatorcontrib><creatorcontrib>Hadjikakou, S.K.</creatorcontrib><title>Innovative material containing the natural product curcumin, with enhanced antimicrobial properties for active packaging</title><title>Materials Science & Engineering C</title><addtitle>Mater Sci Eng C Mater Biol Appl</addtitle><description>Curcumin (Curc) reacts with zinc di‑iodine (ZnI2) in 2:1molar ratio in the presence of an excess of a base triethylamine ((CH3CH2)3N) in methanol (CH3OH) solution towards the amorphous solid material of formula [ZnI2(Curc)2] (1). The complex was characterized by melting point (m.p.), Fourier Transform-Infra Red (FT-IR) and Nuclear Magnetic Resonance of hydrogen nucleus (1H NMR) spectroscopy. The formula of 1 was determined by X-ray fluorescence (XRF) analysis. The retention of the structure in solution was confirmed by 1H NMR spectroscopy.
The antimicrobial activity of the complex has been studied against the bacteria Pseudomonas aeruginosa (PAO1). The Minimum Inhibitory Concentrations (MIC) of the compounds 1 and Curc against P. aeruginosa (PAO1) are: 71.3μΜ (75.3μg/mL) for [ZnI2(Curc)2] and 339μM (125μg/mL) for Curc, respectively. Moreover, the antimicrobial activity of the new material which was diffused in polystyrene against biofilm formed by PAO1 was also calculated.
The amorphous solid material of formula [ZnI2(Curc)2] (1) (Curc=curcumin) was synthesized and characterized. The complex was characterized by m.p., FT-IR and 1H NMR spectroscopy. The antimicrobial activity of the complex and its polystyrene@[ZnI2(Curc)2] have been studied against the bacteria Pseudomonas aeuroginosa. [Display omitted]
•Active packaging•Zinc curcumin materials•Antimicrobial activity</description><subject>Active packaging materials</subject><subject>Amorphous materials</subject><subject>Anti-Infective Agents - chemistry</subject><subject>Anti-Infective Agents - pharmacology</subject><subject>Antiinfectives and antibacterials</subject><subject>Antimicrobial activity</subject><subject>Antimicrobial materials</subject><subject>Biofilms</subject><subject>Biological inorganic chemistry</subject><subject>Biological Products - chemistry</subject><subject>Biological Products - pharmacology</subject><subject>Coordination Complexes - chemical synthesis</subject><subject>Coordination Complexes - chemistry</subject><subject>Coordination Complexes - pharmacology</subject><subject>Curcumin</subject><subject>Curcumin - chemistry</subject><subject>Curcumin - pharmacology</subject><subject>Curcumine</subject><subject>Drug Compounding</subject><subject>Fluorescence</subject><subject>Fourier transforms</subject><subject>Innovations</subject><subject>Iodine</subject><subject>Magnetic Resonance Spectroscopy</subject><subject>Materials science</subject><subject>Melting point</subject><subject>Melting points</subject><subject>Microbial Sensitivity Tests</subject><subject>Minimum inhibitory concentration</subject><subject>Natural products</subject><subject>NMR</subject><subject>NMR spectroscopy</subject><subject>Nuclear magnetic resonance</subject><subject>Packaging</subject><subject>Polystyrene</subject><subject>Polystyrene resins</subject><subject>Polystyrenes - chemistry</subject><subject>Pseudomonas aeruginosa</subject><subject>Pseudomonas aeruginosa - drug effects</subject><subject>Spectroscopy</subject><subject>Spectroscopy, Fourier Transform Infrared</subject><subject>Studies</subject><subject>Triethylamine</subject><subject>X ray fluorescence analysis</subject><subject>X-Ray Diffraction</subject><subject>X-ray fluorescence</subject><subject>Zinc</subject><subject>Zinc - chemistry</subject><issn>0928-4931</issn><issn>1873-0191</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2018</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kb1uFDEUhS1ERJbAC1AgSzQUzOC_2bElGhTxEylSGqitO_adrJcdz2J7Fnh7vNlAkSKVJeu7n6_PIeQVZy1nfP1-204ZXSsY71vOW6b4E7LiupcN44Y_JStmhG6UkfycPM95y9hay148I-fCdNwoblbk91WM8wFKOCCdoGAKsKNujgVCDPGWlg3SCGVJ9XqfZr-4Qt2S3DKF-I7-CmVDMW4gOvQUYglTcGkewoneYyoBMx3nRMHdvbEH9wNuq_kFORthl_Hl_XlBvn_-9O3ya3N98-Xq8uN145TgpenE6IRSQkjsvUTXOaW6zqxHMOCkxqGXHryWWq878J3Q3jvWD7IbBAyyZ_KCvD156z4_F8zFTiE73O0g4rxkW9MThmt2h755gG7nJcW6XaWMUR3TSlZKnKj60ZwTjnafwgTpj-XMHnuxW3vs5WjuLee29lKHXt-rl2FC_3_kXxEV-HACsGZxCJhsdgGPsYaErlg_h8f8fwHuIKDC</recordid><startdate>20180301</startdate><enddate>20180301</enddate><creator>Papadimitriou, A.</creator><creator>Ketikidis, I.</creator><creator>Stathopoulou, M-E.K.</creator><creator>Banti, C.N.</creator><creator>Papachristodoulou, C.</creator><creator>Zoumpoulakis, L.</creator><creator>Agathopoulos, S.</creator><creator>Vagenas, G.V.</creator><creator>Hadjikakou, S.K.</creator><general>Elsevier B.V</general><general>Elsevier BV</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QF</scope><scope>7QO</scope><scope>7QQ</scope><scope>7SC</scope><scope>7SE</scope><scope>7SP</scope><scope>7SR</scope><scope>7T7</scope><scope>7TA</scope><scope>7TB</scope><scope>7U5</scope><scope>8BQ</scope><scope>8FD</scope><scope>C1K</scope><scope>F28</scope><scope>FR3</scope><scope>H8D</scope><scope>H8G</scope><scope>JG9</scope><scope>JQ2</scope><scope>KR7</scope><scope>L7M</scope><scope>L~C</scope><scope>L~D</scope><scope>P64</scope><scope>7X8</scope></search><sort><creationdate>20180301</creationdate><title>Innovative material containing the natural product curcumin, with enhanced antimicrobial properties for active packaging</title><author>Papadimitriou, A. ; Ketikidis, I. ; Stathopoulou, M-E.K. ; Banti, C.N. ; Papachristodoulou, C. ; Zoumpoulakis, L. ; Agathopoulos, S. ; Vagenas, G.V. ; Hadjikakou, S.K.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c421t-52fc244223e7d3ec5c445596fa9ac38eb73dad838865ad528ddc07b35b2ab3703</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2018</creationdate><topic>Active packaging materials</topic><topic>Amorphous materials</topic><topic>Anti-Infective Agents - chemistry</topic><topic>Anti-Infective Agents - pharmacology</topic><topic>Antiinfectives and antibacterials</topic><topic>Antimicrobial activity</topic><topic>Antimicrobial materials</topic><topic>Biofilms</topic><topic>Biological inorganic chemistry</topic><topic>Biological Products - chemistry</topic><topic>Biological Products - pharmacology</topic><topic>Coordination Complexes - chemical synthesis</topic><topic>Coordination Complexes - chemistry</topic><topic>Coordination Complexes - pharmacology</topic><topic>Curcumin</topic><topic>Curcumin - chemistry</topic><topic>Curcumin - pharmacology</topic><topic>Curcumine</topic><topic>Drug Compounding</topic><topic>Fluorescence</topic><topic>Fourier transforms</topic><topic>Innovations</topic><topic>Iodine</topic><topic>Magnetic Resonance Spectroscopy</topic><topic>Materials science</topic><topic>Melting point</topic><topic>Melting points</topic><topic>Microbial Sensitivity Tests</topic><topic>Minimum inhibitory concentration</topic><topic>Natural products</topic><topic>NMR</topic><topic>NMR spectroscopy</topic><topic>Nuclear magnetic resonance</topic><topic>Packaging</topic><topic>Polystyrene</topic><topic>Polystyrene resins</topic><topic>Polystyrenes - chemistry</topic><topic>Pseudomonas aeruginosa</topic><topic>Pseudomonas aeruginosa - drug effects</topic><topic>Spectroscopy</topic><topic>Spectroscopy, Fourier Transform Infrared</topic><topic>Studies</topic><topic>Triethylamine</topic><topic>X ray fluorescence analysis</topic><topic>X-Ray Diffraction</topic><topic>X-ray fluorescence</topic><topic>Zinc</topic><topic>Zinc - chemistry</topic><toplevel>online_resources</toplevel><creatorcontrib>Papadimitriou, A.</creatorcontrib><creatorcontrib>Ketikidis, I.</creatorcontrib><creatorcontrib>Stathopoulou, M-E.K.</creatorcontrib><creatorcontrib>Banti, C.N.</creatorcontrib><creatorcontrib>Papachristodoulou, C.</creatorcontrib><creatorcontrib>Zoumpoulakis, L.</creatorcontrib><creatorcontrib>Agathopoulos, S.</creatorcontrib><creatorcontrib>Vagenas, G.V.</creatorcontrib><creatorcontrib>Hadjikakou, S.K.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Aluminium Industry Abstracts</collection><collection>Biotechnology Research Abstracts</collection><collection>Ceramic Abstracts</collection><collection>Computer and Information Systems Abstracts</collection><collection>Corrosion Abstracts</collection><collection>Electronics & Communications Abstracts</collection><collection>Engineered Materials Abstracts</collection><collection>Industrial and Applied Microbiology Abstracts (Microbiology A)</collection><collection>Materials Business File</collection><collection>Mechanical & Transportation Engineering Abstracts</collection><collection>Solid State and Superconductivity Abstracts</collection><collection>METADEX</collection><collection>Technology Research Database</collection><collection>Environmental Sciences and Pollution Management</collection><collection>ANTE: Abstracts in New Technology & Engineering</collection><collection>Engineering Research Database</collection><collection>Aerospace Database</collection><collection>Copper Technical Reference Library</collection><collection>Materials Research Database</collection><collection>ProQuest Computer Science Collection</collection><collection>Civil Engineering Abstracts</collection><collection>Advanced Technologies Database with Aerospace</collection><collection>Computer and Information Systems Abstracts Academic</collection><collection>Computer and Information Systems Abstracts Professional</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>Materials Science & Engineering C</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Papadimitriou, A.</au><au>Ketikidis, I.</au><au>Stathopoulou, M-E.K.</au><au>Banti, C.N.</au><au>Papachristodoulou, C.</au><au>Zoumpoulakis, L.</au><au>Agathopoulos, S.</au><au>Vagenas, G.V.</au><au>Hadjikakou, S.K.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Innovative material containing the natural product curcumin, with enhanced antimicrobial properties for active packaging</atitle><jtitle>Materials Science & Engineering C</jtitle><addtitle>Mater Sci Eng C Mater Biol Appl</addtitle><date>2018-03-01</date><risdate>2018</risdate><volume>84</volume><spage>118</spage><epage>122</epage><pages>118-122</pages><issn>0928-4931</issn><eissn>1873-0191</eissn><abstract>Curcumin (Curc) reacts with zinc di‑iodine (ZnI2) in 2:1molar ratio in the presence of an excess of a base triethylamine ((CH3CH2)3N) in methanol (CH3OH) solution towards the amorphous solid material of formula [ZnI2(Curc)2] (1). The complex was characterized by melting point (m.p.), Fourier Transform-Infra Red (FT-IR) and Nuclear Magnetic Resonance of hydrogen nucleus (1H NMR) spectroscopy. The formula of 1 was determined by X-ray fluorescence (XRF) analysis. The retention of the structure in solution was confirmed by 1H NMR spectroscopy.
The antimicrobial activity of the complex has been studied against the bacteria Pseudomonas aeruginosa (PAO1). The Minimum Inhibitory Concentrations (MIC) of the compounds 1 and Curc against P. aeruginosa (PAO1) are: 71.3μΜ (75.3μg/mL) for [ZnI2(Curc)2] and 339μM (125μg/mL) for Curc, respectively. Moreover, the antimicrobial activity of the new material which was diffused in polystyrene against biofilm formed by PAO1 was also calculated.
The amorphous solid material of formula [ZnI2(Curc)2] (1) (Curc=curcumin) was synthesized and characterized. The complex was characterized by m.p., FT-IR and 1H NMR spectroscopy. The antimicrobial activity of the complex and its polystyrene@[ZnI2(Curc)2] have been studied against the bacteria Pseudomonas aeuroginosa. [Display omitted]
•Active packaging•Zinc curcumin materials•Antimicrobial activity</abstract><cop>Netherlands</cop><pub>Elsevier B.V</pub><pmid>29519419</pmid><doi>10.1016/j.msec.2017.11.041</doi><tpages>5</tpages></addata></record> |
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| ispartof | Materials Science & Engineering C, 2018-03, Vol.84, p.118-122 |
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| subjects | Active packaging materials Amorphous materials Anti-Infective Agents - chemistry Anti-Infective Agents - pharmacology Antiinfectives and antibacterials Antimicrobial activity Antimicrobial materials Biofilms Biological inorganic chemistry Biological Products - chemistry Biological Products - pharmacology Coordination Complexes - chemical synthesis Coordination Complexes - chemistry Coordination Complexes - pharmacology Curcumin Curcumin - chemistry Curcumin - pharmacology Curcumine Drug Compounding Fluorescence Fourier transforms Innovations Iodine Magnetic Resonance Spectroscopy Materials science Melting point Melting points Microbial Sensitivity Tests Minimum inhibitory concentration Natural products NMR NMR spectroscopy Nuclear magnetic resonance Packaging Polystyrene Polystyrene resins Polystyrenes - chemistry Pseudomonas aeruginosa Pseudomonas aeruginosa - drug effects Spectroscopy Spectroscopy, Fourier Transform Infrared Studies Triethylamine X ray fluorescence analysis X-Ray Diffraction X-ray fluorescence Zinc Zinc - chemistry |
| title | Innovative material containing the natural product curcumin, with enhanced antimicrobial properties for active packaging |
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